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International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19
STATEMENT: The International Society for Cellular and Gene Therapies (ISCT) and the International Society for Extracellular Vesicles (ISEV) recognize the potential of extracellular vesicles (EVs, including exosomes) from mesenchymal stromal cells (MSCs) and possibly other cell sources as treatments...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Society for Cell and Gene Therapy.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229942/ https://www.ncbi.nlm.nih.gov/pubmed/32425691 http://dx.doi.org/10.1016/j.jcyt.2020.05.002 |
| _version_ | 1783534855759331328 |
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| author | Börger, Verena Weiss, Daniel J. Anderson, Johnathon D. Borràs, Francesc E. Bussolati, Benedetta Carter, David R.F. Dominici, Massimo Falcón-Pérez, Juan M. Gimona, Mario Hill, Andrew F. Hoffman, Andrew M. de Kleijn, Dominique Levine, Bruce L. Lim, Rebecca Lötvall, Jan Mitsialis, S. Alex Monguió-Tortajada, Marta Muraca, Maurizio Nieuwland, Rienk Nowocin, Anna O'Driscoll, Lorraine Ortiz, Luis A. Phinney, Donald G Reischl, Ilona Rohde, Eva Sanzenbacher, Ralf Théry, Clotilde Toh, Wei Seong Witwer, Kenneth W. Lim, Sai Kiang Giebel, Bernd |
| author_facet | Börger, Verena Weiss, Daniel J. Anderson, Johnathon D. Borràs, Francesc E. Bussolati, Benedetta Carter, David R.F. Dominici, Massimo Falcón-Pérez, Juan M. Gimona, Mario Hill, Andrew F. Hoffman, Andrew M. de Kleijn, Dominique Levine, Bruce L. Lim, Rebecca Lötvall, Jan Mitsialis, S. Alex Monguió-Tortajada, Marta Muraca, Maurizio Nieuwland, Rienk Nowocin, Anna O'Driscoll, Lorraine Ortiz, Luis A. Phinney, Donald G Reischl, Ilona Rohde, Eva Sanzenbacher, Ralf Théry, Clotilde Toh, Wei Seong Witwer, Kenneth W. Lim, Sai Kiang Giebel, Bernd |
| author_sort | Börger, Verena |
| collection | PubMed |
| description | STATEMENT: The International Society for Cellular and Gene Therapies (ISCT) and the International Society for Extracellular Vesicles (ISEV) recognize the potential of extracellular vesicles (EVs, including exosomes) from mesenchymal stromal cells (MSCs) and possibly other cell sources as treatments for COVID-19. Research and trials in this area are encouraged. However, ISEV and ISCT do not currently endorse the use of EVs or exosomes for any purpose in COVID-19, including but not limited to reducing cytokine storm, exerting regenerative effects or delivering drugs, pending the generation of appropriate manufacturing and quality control provisions, pre-clinical safety and efficacy data, rational clinical trial design and proper regulatory oversight. |
| format | Online Article Text |
| id | pubmed-7229942 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | International Society for Cell and Gene Therapy. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-72299422020-05-18 International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 Börger, Verena Weiss, Daniel J. Anderson, Johnathon D. Borràs, Francesc E. Bussolati, Benedetta Carter, David R.F. Dominici, Massimo Falcón-Pérez, Juan M. Gimona, Mario Hill, Andrew F. Hoffman, Andrew M. de Kleijn, Dominique Levine, Bruce L. Lim, Rebecca Lötvall, Jan Mitsialis, S. Alex Monguió-Tortajada, Marta Muraca, Maurizio Nieuwland, Rienk Nowocin, Anna O'Driscoll, Lorraine Ortiz, Luis A. Phinney, Donald G Reischl, Ilona Rohde, Eva Sanzenbacher, Ralf Théry, Clotilde Toh, Wei Seong Witwer, Kenneth W. Lim, Sai Kiang Giebel, Bernd Cytotherapy Article STATEMENT: The International Society for Cellular and Gene Therapies (ISCT) and the International Society for Extracellular Vesicles (ISEV) recognize the potential of extracellular vesicles (EVs, including exosomes) from mesenchymal stromal cells (MSCs) and possibly other cell sources as treatments for COVID-19. Research and trials in this area are encouraged. However, ISEV and ISCT do not currently endorse the use of EVs or exosomes for any purpose in COVID-19, including but not limited to reducing cytokine storm, exerting regenerative effects or delivering drugs, pending the generation of appropriate manufacturing and quality control provisions, pre-clinical safety and efficacy data, rational clinical trial design and proper regulatory oversight. International Society for Cell and Gene Therapy. 2020-09 2020-05-16 /pmc/articles/PMC7229942/ /pubmed/32425691 http://dx.doi.org/10.1016/j.jcyt.2020.05.002 Text en © 2020 International Society for Cell and Gene Therapy. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Article Börger, Verena Weiss, Daniel J. Anderson, Johnathon D. Borràs, Francesc E. Bussolati, Benedetta Carter, David R.F. Dominici, Massimo Falcón-Pérez, Juan M. Gimona, Mario Hill, Andrew F. Hoffman, Andrew M. de Kleijn, Dominique Levine, Bruce L. Lim, Rebecca Lötvall, Jan Mitsialis, S. Alex Monguió-Tortajada, Marta Muraca, Maurizio Nieuwland, Rienk Nowocin, Anna O'Driscoll, Lorraine Ortiz, Luis A. Phinney, Donald G Reischl, Ilona Rohde, Eva Sanzenbacher, Ralf Théry, Clotilde Toh, Wei Seong Witwer, Kenneth W. Lim, Sai Kiang Giebel, Bernd International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 |
| title | International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 |
| title_full | International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 |
| title_fullStr | International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 |
| title_full_unstemmed | International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 |
| title_short | International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 |
| title_sort | international society for extracellular vesicles and international society for cell and gene therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229942/ https://www.ncbi.nlm.nih.gov/pubmed/32425691 http://dx.doi.org/10.1016/j.jcyt.2020.05.002 |
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