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Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential
Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source of high value-added compounds...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230368/ https://www.ncbi.nlm.nih.gov/pubmed/32276401 http://dx.doi.org/10.3390/md18040197 |
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author | Saadaoui, Imen Rasheed, Rihab Abdulrahman, Nabeel Bounnit, Touria Cherif, Maroua Al Jabri, Hareb Mraiche, Fatima |
author_facet | Saadaoui, Imen Rasheed, Rihab Abdulrahman, Nabeel Bounnit, Touria Cherif, Maroua Al Jabri, Hareb Mraiche, Fatima |
author_sort | Saadaoui, Imen |
collection | PubMed |
description | Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source of high value-added compounds are considered as very promising source of these bioactive molecules. These are secondary metabolites that consist mainly of derivatives of peptides, carbohydrates, and lipids with various structures. Accordingly, various mechanisms by which different algae molecules demonstrate attenuation of tumor angiogenesis were stated and discussed. The mode of action of the algae bioactives is closely related to their nature and chemical structure. Furthermore, this literature review considers the synergistic effect between microalgae bioactives and conventional drugs and discuss the economic feasibility of producing microalgae bioactives at large scale to conclude with some future perspectives related to algae-based drug discovery. |
format | Online Article Text |
id | pubmed-7230368 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72303682020-05-22 Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential Saadaoui, Imen Rasheed, Rihab Abdulrahman, Nabeel Bounnit, Touria Cherif, Maroua Al Jabri, Hareb Mraiche, Fatima Mar Drugs Review Lung cancer is one of the major causes of death worldwide. Natural molecules with anti-lung cancer potential are of a great interest and considered as very promising alternative to substitute or enhance the efficiency of the conventional drugs. Recently, algae as source of high value-added compounds are considered as very promising source of these bioactive molecules. These are secondary metabolites that consist mainly of derivatives of peptides, carbohydrates, and lipids with various structures. Accordingly, various mechanisms by which different algae molecules demonstrate attenuation of tumor angiogenesis were stated and discussed. The mode of action of the algae bioactives is closely related to their nature and chemical structure. Furthermore, this literature review considers the synergistic effect between microalgae bioactives and conventional drugs and discuss the economic feasibility of producing microalgae bioactives at large scale to conclude with some future perspectives related to algae-based drug discovery. MDPI 2020-04-08 /pmc/articles/PMC7230368/ /pubmed/32276401 http://dx.doi.org/10.3390/md18040197 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Saadaoui, Imen Rasheed, Rihab Abdulrahman, Nabeel Bounnit, Touria Cherif, Maroua Al Jabri, Hareb Mraiche, Fatima Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
title | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
title_full | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
title_fullStr | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
title_full_unstemmed | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
title_short | Algae-Derived Bioactive Compounds with Anti-Lung Cancer Potential |
title_sort | algae-derived bioactive compounds with anti-lung cancer potential |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230368/ https://www.ncbi.nlm.nih.gov/pubmed/32276401 http://dx.doi.org/10.3390/md18040197 |
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