Cargando…

Dermatopontin, A Novel Adipokine Promoting Adipose Tissue Extracellular Matrix Remodelling and Inflammation in Obesity †

Compelling evidence suggests that dermatopontin (DPT) regulates collagen and fibronectin fibril formation, the induction of cell adhesion and the prompting of wound healing. We aimed to evaluate the role of DPT on obesity and its associated metabolic alterations as well as its impact in visceral adi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Unamuno, Xabier, Gómez-Ambrosi, Javier, Ramírez, Beatriz, Rodríguez, Amaia, Becerril, Sara, Valentí, Víctor, Moncada, Rafael, Silva, Camilo, Salvador, Javier, Frühbeck, Gema, Catalán, Victoria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230369/ https://www.ncbi.nlm.nih.gov/pubmed/32283761 http://dx.doi.org/10.3390/jcm9041069

Ejemplares similares

Dermatopontin Influences the Development of Obesity-Associated Colon Cancer by Changes in the Expression of Extracellular Matrix Proteins
por: Catalán, Victoria, et al.
Publicado: (2022)

Decreased Levels of Microfibril-Associated Glycoprotein (MAGP)-1 in Patients with Colon Cancer and Obesity Are Associated with Changes in Extracellular Matrix Remodelling
por: Gómez de Segura, Iranzu, et al.
Publicado: (2021)

Netrin-1 Promotes Visceral Adipose Tissue Inflammation in Obesity and Is Associated with Insulin Resistance
por: Mentxaka, Amaia, et al.
Publicado: (2022)

Improved Adipose Tissue Function after Single Anastomosis Duodeno-Ileal Bypass with Sleeve-Gastrectomy (SADI-S) in Diet-Induced Obesity
por: Becerril, Sara, et al.
Publicado: (2022)

Increase of the Adiponectin/Leptin Ratio in Patients with Obesity and Type 2 Diabetes after Roux-en-Y Gastric Bypass
por: Unamuno, Xabier, et al.
Publicado: (2019)

Osteopontin Deletion Prevents the Development of Obesity and Hepatic Steatosis via Impaired Adipose Tissue Matrix Remodeling and Reduced Inflammation and Fibrosis in Adipose Tissue and Liver in Mice
por: Lancha, Andoni, et al.
Publicado: (2014)

Serum Levels of IL-1 RA Increase with Obesity and Type 2 Diabetes in Relation to Adipose Tissue Dysfunction and are Reduced After Bariatric Surgery in Parallel to Adiposity
por: Frühbeck, Gema, et al.
Publicado: (2022)

iNOS Gene Ablation Prevents Liver Fibrosis in Leptin-Deficient ob/ob Mice
por: Becerril, Sara, et al.
Publicado: (2019)

Increased Levels of Interleukin-36 in Obesity and Type 2 Diabetes Fuel Adipose Tissue Inflammation by Inducing Its Own Expression and Release by Adipocytes and Macrophages
por: Frühbeck, Gema, et al.
Publicado: (2022)

Corrigendum: Increased levels of interleukin-36 in obesity and type 2 diabetes fuels adipose tissue inflammation by inducing its own expression and release by adipocytes and macrophages
por: Frühbeck, Gema, et al.
Publicado: (2023)

GLP-1 Limits Adipocyte Inflammation and Its Low Circulating Pre-Operative Concentrations Predict Worse Type 2 Diabetes Remission after Bariatric Surgery in Obese Patients
por: Izaguirre, Maitane, et al.
Publicado: (2019)

The Differential Expression of the Inflammasomes in Adipose Tissue and Colon Influences the Development of Colon Cancer in a Context of Obesity by Regulating Intestinal Inflammation
por: Frühbeck, Gema, et al.
Publicado: (2021)

Functional Relationship between Leptin and Nitric Oxide in Metabolism
por: Becerril, Sara, et al.
Publicado: (2019)

Adiponectin-leptin Ratio is a Functional Biomarker of Adipose Tissue Inflammation
por: Frühbeck, Gema, et al.
Publicado: (2019)

Increased Obesity-Associated Circulating Levels of the Extracellular Matrix Proteins Osteopontin, Chitinase-3 Like-1 and Tenascin C Are Associated with Colon Cancer
por: Catalán, Victoria, et al.
Publicado: (2016)

FNDC4 and FNDC5 reduce SARS-CoV-2 entry points and spike glycoprotein S1-induced pyroptosis, apoptosis, and necroptosis in human adipocytes
por: Frühbeck, Gema, et al.
Publicado: (2021)

Adipose tissue immunity and cancer
por: Catalán, Victoria, et al.
Publicado: (2013)

Increased Expression Levels of Netrin-1 in Visceral Adipose Tissue during Obesity Favour Colon Cancer Cell Migration
por: Mentxaka, Amaia, et al.
Publicado: (2023)

Acylated and desacyl ghrelin are associated with hepatic lipogenesis, β-oxidation and autophagy: role in NAFLD amelioration after sleeve gastrectomy in obese rats
por: Ezquerro, Silvia, et al.
Publicado: (2016)

Deletion of Inducible Nitric-Oxide Synthase in Leptin-Deficient Mice Improves Brown Adipose Tissue Function
por: Becerril, Sara, et al.
Publicado: (2010)

Increased Aquaporin-7 Expression Is Associated with Changes in Rat Brown Adipose Tissue Whitening in Obesity: Impact of Cold Exposure and Bariatric Surgery
por: Frühbeck, Gema, et al.
Publicado: (2023)

Mechanisms Linking Excess Adiposity and Carcinogenesis Promotion
por: Pérez-Hernández, Ana I., et al.
Publicado: (2014)

Involvement of the leptin-adiponectin axis in inflammation and oxidative stress in the metabolic syndrome
por: Frühbeck, Gema, et al.
Publicado: (2017)

Leptin Administration Downregulates the Increased Expression Levels of Genes Related to Oxidative Stress and Inflammation in the Skeletal Muscle of ob/ob Mice
por: Sáinz, Neira, et al.
Publicado: (2010)

Leptin Administration Favors Muscle Mass Accretion by Decreasing FoxO3a and Increasing PGC-1α in ob/ob Mice
por: Sáinz, Neira, et al.
Publicado: (2009)

Normalization of adiponectin concentrations by leptin replacement in ob/ob mice is accompanied by reductions in systemic oxidative stress and inflammation
por: Frühbeck, Gema, et al.
Publicado: (2017)

Sex- and Age-Dependent Changes in the Adiponectin/Leptin Ratio in Experimental Diet-Induced Obesity in Mice
por: Becerril, Sara, et al.
Publicado: (2022)

Effect of guanylin peptides on pancreas steatosis and function in experimental diet-induced obesity and after bariatric surgery
por: Otero, Aarón, et al.
Publicado: (2023)

BMI-based obesity classification misses children and adolescents with raised cardiometabolic risk due to increased adiposity
por: Zapata, J. Karina, et al.
Publicado: (2023)

Aquaporin-11 Contributes to TGF-β1-induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation
por: Frühbeck, Gema, et al.
Publicado: (2020)

Dermatopontin in Skeletal Muscle Extracellular Matrix Regulates Myogenesis
por: Kim, Taeyeon, et al.
Publicado: (2019)

Role of ANGPTL8 in NAFLD Improvement after Bariatric Surgery in Experimental and Human Obesity
por: Perdomo, Carolina M., et al.
Publicado: (2021)

Clinical Usefulness of a New Equation for Estimating Body Fat
por: Gómez-Ambrosi, Javier, et al.
Publicado: (2012)

Circulating GDF11 levels are decreased with age but are unchanged with obesity and type 2 diabetes
por: Añón-Hidalgo, Juan, et al.
Publicado: (2019)

Leptin Reduces the Expression and Increases the Phosphorylation of the Negative Regulators of GLUT4 Traffic TBC1D1 and TBC1D4 in Muscle of ob/ob Mice
por: Sáinz, Neira, et al.
Publicado: (2012)

Leptin Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by Angiotensin II through Nitric Oxide-Dependent Mechanisms
por: Rodríguez, Amaia, et al.
Publicado: (2010)

Resting Energy Expenditure Is Not Altered in Children and Adolescents with Obesity. Effect of Age and Gender and Association with Serum Leptin Levels
por: Zapata, J. Karina, et al.
Publicado: (2021)

Caloric Restriction Prevents Metabolic Dysfunction and the Changes in Hypothalamic Neuropeptides Associated with Obesity Independently of Dietary Fat Content in Rats
por: Martín, Marina, et al.
Publicado: (2021)

Circulating Concentrations of GDF11 are Positively Associated with TSH Levels in Humans
por: Añón-Hidalgo, Juan, et al.
Publicado: (2019)

Leptin administration restores the altered adipose and hepatic expression of aquaglyceroporins improving the non-alcoholic fatty liver of ob/ob mice
por: Rodríguez, Amaia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rjpv8irb1asooguf9j8dl5dqfi