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Synchronous Cervical Adenocarcinoma and Ovarian Serous Adenocarcinoma—A Case Report and Literature Review

Background/Aim: Synchronous gynecological malignancies are rarely encountered, and most often these cases are represented by synchronous ovarian and endometrial cancer. The aim of this paper is to present the case of a 53-year-old patient who was diagnosed with synchronous cervical and ovarian cance...

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Autores principales: Bacalbasa, Nicolae, Balescu, Irina Cecilia, Diaconu, Camelia, Dima, Simona, Iliescu, Laura, Vilcu, Mihaela, Filipescu, Alexandru, Halmaciu, Ioana, Cretoiu, Dragos, Brezean, Iulian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230379/
https://www.ncbi.nlm.nih.gov/pubmed/32235322
http://dx.doi.org/10.3390/medicina56040152
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author Bacalbasa, Nicolae
Balescu, Irina Cecilia
Diaconu, Camelia
Dima, Simona
Iliescu, Laura
Vilcu, Mihaela
Filipescu, Alexandru
Halmaciu, Ioana
Cretoiu, Dragos
Brezean, Iulian
author_facet Bacalbasa, Nicolae
Balescu, Irina Cecilia
Diaconu, Camelia
Dima, Simona
Iliescu, Laura
Vilcu, Mihaela
Filipescu, Alexandru
Halmaciu, Ioana
Cretoiu, Dragos
Brezean, Iulian
author_sort Bacalbasa, Nicolae
collection PubMed
description Background/Aim: Synchronous gynecological malignancies are rarely encountered, and most often these cases are represented by synchronous ovarian and endometrial cancer. The aim of this paper is to present the case of a 53-year-old patient who was diagnosed with synchronous cervical and ovarian cancer. Case presentation: The patient had been initially investigated for vaginal bleeding and was submitted to a biopsy confirming the presence of a cervical adenocarcinoma. Once the diagnostic of malignancy was confirmed, the patient was submitted to a computed tomography which revealed the presence of large abdominal tumoral nodules of peritoneal carcinomatosis and was submitted to palliative chemotherapy with poor response. Eighteen months later she developed intestinal obstruction and was submitted to surgery. At that moment, synchronous ovarian and cervical tumors were diagnosed. Total radical hysterectomy with bilateral adnexectomy, pelvic and para-aortic lymph node dissection, omentectomy, and pelvic peritonectomy was performed; in the meantime, the histopathological studies confirmed the presence of two synchronous malignancies. Conclusion: Although synchronous lesions are rarely encountered, this eventuality should not be omitted. In such cases, surgery should be taken in consideration and the intent of radicality should regard both lesions.
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spelling pubmed-72303792020-05-22 Synchronous Cervical Adenocarcinoma and Ovarian Serous Adenocarcinoma—A Case Report and Literature Review Bacalbasa, Nicolae Balescu, Irina Cecilia Diaconu, Camelia Dima, Simona Iliescu, Laura Vilcu, Mihaela Filipescu, Alexandru Halmaciu, Ioana Cretoiu, Dragos Brezean, Iulian Medicina (Kaunas) Case Report Background/Aim: Synchronous gynecological malignancies are rarely encountered, and most often these cases are represented by synchronous ovarian and endometrial cancer. The aim of this paper is to present the case of a 53-year-old patient who was diagnosed with synchronous cervical and ovarian cancer. Case presentation: The patient had been initially investigated for vaginal bleeding and was submitted to a biopsy confirming the presence of a cervical adenocarcinoma. Once the diagnostic of malignancy was confirmed, the patient was submitted to a computed tomography which revealed the presence of large abdominal tumoral nodules of peritoneal carcinomatosis and was submitted to palliative chemotherapy with poor response. Eighteen months later she developed intestinal obstruction and was submitted to surgery. At that moment, synchronous ovarian and cervical tumors were diagnosed. Total radical hysterectomy with bilateral adnexectomy, pelvic and para-aortic lymph node dissection, omentectomy, and pelvic peritonectomy was performed; in the meantime, the histopathological studies confirmed the presence of two synchronous malignancies. Conclusion: Although synchronous lesions are rarely encountered, this eventuality should not be omitted. In such cases, surgery should be taken in consideration and the intent of radicality should regard both lesions. MDPI 2020-03-29 /pmc/articles/PMC7230379/ /pubmed/32235322 http://dx.doi.org/10.3390/medicina56040152 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Bacalbasa, Nicolae
Balescu, Irina Cecilia
Diaconu, Camelia
Dima, Simona
Iliescu, Laura
Vilcu, Mihaela
Filipescu, Alexandru
Halmaciu, Ioana
Cretoiu, Dragos
Brezean, Iulian
Synchronous Cervical Adenocarcinoma and Ovarian Serous Adenocarcinoma—A Case Report and Literature Review
title Synchronous Cervical Adenocarcinoma and Ovarian Serous Adenocarcinoma—A Case Report and Literature Review
title_full Synchronous Cervical Adenocarcinoma and Ovarian Serous Adenocarcinoma—A Case Report and Literature Review
title_fullStr Synchronous Cervical Adenocarcinoma and Ovarian Serous Adenocarcinoma—A Case Report and Literature Review
title_full_unstemmed Synchronous Cervical Adenocarcinoma and Ovarian Serous Adenocarcinoma—A Case Report and Literature Review
title_short Synchronous Cervical Adenocarcinoma and Ovarian Serous Adenocarcinoma—A Case Report and Literature Review
title_sort synchronous cervical adenocarcinoma and ovarian serous adenocarcinoma—a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230379/
https://www.ncbi.nlm.nih.gov/pubmed/32235322
http://dx.doi.org/10.3390/medicina56040152
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