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The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis

The treatment of choice for dermatitis herpetiformis (DH), a cutaneous manifestation of coeliac disease, is a life-long gluten-free diet (GFD). In a GFD, wheat, rye and barley should be strictly avoided, but the role of oats is more controversial. This study aimed to investigate the safety and long-...

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Autores principales: Alakoski, Anna, Hervonen, Kaisa, Mansikka, Eriika, Reunala, Timo, Kaukinen, Katri, Kivelä, Laura, Laurikka, Pilvi, Huhtala, Heini, Kurppa, Kalle, Salmi, Teea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230654/
https://www.ncbi.nlm.nih.gov/pubmed/32290504
http://dx.doi.org/10.3390/nu12041060
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author Alakoski, Anna
Hervonen, Kaisa
Mansikka, Eriika
Reunala, Timo
Kaukinen, Katri
Kivelä, Laura
Laurikka, Pilvi
Huhtala, Heini
Kurppa, Kalle
Salmi, Teea
author_facet Alakoski, Anna
Hervonen, Kaisa
Mansikka, Eriika
Reunala, Timo
Kaukinen, Katri
Kivelä, Laura
Laurikka, Pilvi
Huhtala, Heini
Kurppa, Kalle
Salmi, Teea
author_sort Alakoski, Anna
collection PubMed
description The treatment of choice for dermatitis herpetiformis (DH), a cutaneous manifestation of coeliac disease, is a life-long gluten-free diet (GFD). In a GFD, wheat, rye and barley should be strictly avoided, but the role of oats is more controversial. This study aimed to investigate the safety and long-term quality of life and health effects of oat consumption in 312 long-term treated DH patients. Baseline data were gathered from patient records and follow-up data from questionnaires or interviews, and validated questionnaires were used to assess quality of life. We found that altogether 256 patients (82%) were consuming oats as part of their GFD at the follow-up. Long-term follow-up data showed that there were no differences in the presence of long-term illnesses, coeliac disease complications or the usage of medication between those consuming and not consuming oats. However, oat consumers had a better quality of life and reported ongoing gastrointestinal symptoms less frequently (4% vs 19%, p = 0.004) at the follow-up than those not consuming oats. The study established that oats are safe for DH patients and in the long-term seem to improve the quality of life of DH patients.
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spelling pubmed-72306542020-05-22 The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis Alakoski, Anna Hervonen, Kaisa Mansikka, Eriika Reunala, Timo Kaukinen, Katri Kivelä, Laura Laurikka, Pilvi Huhtala, Heini Kurppa, Kalle Salmi, Teea Nutrients Article The treatment of choice for dermatitis herpetiformis (DH), a cutaneous manifestation of coeliac disease, is a life-long gluten-free diet (GFD). In a GFD, wheat, rye and barley should be strictly avoided, but the role of oats is more controversial. This study aimed to investigate the safety and long-term quality of life and health effects of oat consumption in 312 long-term treated DH patients. Baseline data were gathered from patient records and follow-up data from questionnaires or interviews, and validated questionnaires were used to assess quality of life. We found that altogether 256 patients (82%) were consuming oats as part of their GFD at the follow-up. Long-term follow-up data showed that there were no differences in the presence of long-term illnesses, coeliac disease complications or the usage of medication between those consuming and not consuming oats. However, oat consumers had a better quality of life and reported ongoing gastrointestinal symptoms less frequently (4% vs 19%, p = 0.004) at the follow-up than those not consuming oats. The study established that oats are safe for DH patients and in the long-term seem to improve the quality of life of DH patients. MDPI 2020-04-11 /pmc/articles/PMC7230654/ /pubmed/32290504 http://dx.doi.org/10.3390/nu12041060 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alakoski, Anna
Hervonen, Kaisa
Mansikka, Eriika
Reunala, Timo
Kaukinen, Katri
Kivelä, Laura
Laurikka, Pilvi
Huhtala, Heini
Kurppa, Kalle
Salmi, Teea
The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis
title The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis
title_full The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis
title_fullStr The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis
title_full_unstemmed The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis
title_short The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis
title_sort long-term safety and quality of life effects of oats in dermatitis herpetiformis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230654/
https://www.ncbi.nlm.nih.gov/pubmed/32290504
http://dx.doi.org/10.3390/nu12041060
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