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Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context
This review examines the current state of knowledge regarding toxins from anthozoans (sea anemones, coral, zoanthids, corallimorphs, sea pens and tube anemones). We provide an overview of venom from phylum Cnidaria and review the diversity of venom composition between the two major clades (Medusozoa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230708/ https://www.ncbi.nlm.nih.gov/pubmed/32283847 http://dx.doi.org/10.3390/md18040202 |
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author | Ashwood, Lauren M. Norton, Raymond S. Undheim, Eivind A. B. Hurwood, David A. Prentis, Peter J. |
author_facet | Ashwood, Lauren M. Norton, Raymond S. Undheim, Eivind A. B. Hurwood, David A. Prentis, Peter J. |
author_sort | Ashwood, Lauren M. |
collection | PubMed |
description | This review examines the current state of knowledge regarding toxins from anthozoans (sea anemones, coral, zoanthids, corallimorphs, sea pens and tube anemones). We provide an overview of venom from phylum Cnidaria and review the diversity of venom composition between the two major clades (Medusozoa and Anthozoa). We highlight that the functional and ecological context of venom has implications for the temporal and spatial expression of protein and peptide toxins within class Anthozoa. Understanding the nuances in the regulation of venom arsenals has been made possible by recent advances in analytical technologies that allow characterisation of the spatial distributions of toxins. Furthermore, anthozoans are unique in that ecological roles can be assigned using tissue expression data, thereby circumventing some of the challenges related to pharmacological screening. |
format | Online Article Text |
id | pubmed-7230708 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72307082020-05-22 Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context Ashwood, Lauren M. Norton, Raymond S. Undheim, Eivind A. B. Hurwood, David A. Prentis, Peter J. Mar Drugs Review This review examines the current state of knowledge regarding toxins from anthozoans (sea anemones, coral, zoanthids, corallimorphs, sea pens and tube anemones). We provide an overview of venom from phylum Cnidaria and review the diversity of venom composition between the two major clades (Medusozoa and Anthozoa). We highlight that the functional and ecological context of venom has implications for the temporal and spatial expression of protein and peptide toxins within class Anthozoa. Understanding the nuances in the regulation of venom arsenals has been made possible by recent advances in analytical technologies that allow characterisation of the spatial distributions of toxins. Furthermore, anthozoans are unique in that ecological roles can be assigned using tissue expression data, thereby circumventing some of the challenges related to pharmacological screening. MDPI 2020-04-09 /pmc/articles/PMC7230708/ /pubmed/32283847 http://dx.doi.org/10.3390/md18040202 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Ashwood, Lauren M. Norton, Raymond S. Undheim, Eivind A. B. Hurwood, David A. Prentis, Peter J. Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
title | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
title_full | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
title_fullStr | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
title_full_unstemmed | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
title_short | Characterising Functional Venom Profiles of Anthozoans and Medusozoans within Their Ecological Context |
title_sort | characterising functional venom profiles of anthozoans and medusozoans within their ecological context |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230708/ https://www.ncbi.nlm.nih.gov/pubmed/32283847 http://dx.doi.org/10.3390/md18040202 |
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