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Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients
Introduction: The purpose of this paper is to study the type, the clinical presentation, and the best diagnostic methods for pleural solitary fibrous tumors (PSFTs), as well as to evaluate which is the most appropriate treatment, especially as PSFTs represent a rare occurrence in the thoracic pathol...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230748/ https://www.ncbi.nlm.nih.gov/pubmed/32316178 http://dx.doi.org/10.3390/medicina56040185 |
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author | Savu, Cornel Melinte, Alexandru Posea, Radu Galie, Niculae Balescu, Irina Diaconu, Camelia Cretoiu, Dragos Dima, Simona Filipescu, Alexandru Balalau, Cristian Bacalbasa, Nicolae |
author_facet | Savu, Cornel Melinte, Alexandru Posea, Radu Galie, Niculae Balescu, Irina Diaconu, Camelia Cretoiu, Dragos Dima, Simona Filipescu, Alexandru Balalau, Cristian Bacalbasa, Nicolae |
author_sort | Savu, Cornel |
collection | PubMed |
description | Introduction: The purpose of this paper is to study the type, the clinical presentation, and the best diagnostic methods for pleural solitary fibrous tumors (PSFTs), as well as to evaluate which is the most appropriate treatment, especially as PSFTs represent a rare occurrence in the thoracic pathology. Material and Method: A retrospective study was conducted on a group of 45 patients submitted to surgery between January 2015 and December 2019. In most cases, the diagnosis was established through imaging studies—thoracic computed tomography (CT) scan with or without contrast—but also using magnetic resonance imaging (MRI) or positron emission tomography (PET) scans when data from CT scans were scarce. All patients were submitted to surgery with curative intent. Results: Most patients included in this study were asymptomatic, with this pathology being more common in patients over 60 years of age, and more common in women. The occurrence of malignant PSFT in our study was 17.77% (8 cases). All cases were submitted to surgery with curative intent, with a single case developing further recurrence. In order to achieve complete resection en bloc resection of the tumor with the chest wall, resection was performed in two cases, while lower lobectomy, pneumectomy, and hemidiaphragm resection, respectively, were needed in each case. Postoperative mortality was null. Conclusion: Thoracic CT scan remains the most important imagistic investigation in diagnosing. MRI is superior to thoracic CT, especially in cases that involved the larger blood vessels within the thorax, spinal column, or diaphragm. Complete surgical resection is the gold standard in treatment of PSFT, and the prognosis in benign cases is very good. |
format | Online Article Text |
id | pubmed-7230748 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72307482020-05-22 Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients Savu, Cornel Melinte, Alexandru Posea, Radu Galie, Niculae Balescu, Irina Diaconu, Camelia Cretoiu, Dragos Dima, Simona Filipescu, Alexandru Balalau, Cristian Bacalbasa, Nicolae Medicina (Kaunas) Article Introduction: The purpose of this paper is to study the type, the clinical presentation, and the best diagnostic methods for pleural solitary fibrous tumors (PSFTs), as well as to evaluate which is the most appropriate treatment, especially as PSFTs represent a rare occurrence in the thoracic pathology. Material and Method: A retrospective study was conducted on a group of 45 patients submitted to surgery between January 2015 and December 2019. In most cases, the diagnosis was established through imaging studies—thoracic computed tomography (CT) scan with or without contrast—but also using magnetic resonance imaging (MRI) or positron emission tomography (PET) scans when data from CT scans were scarce. All patients were submitted to surgery with curative intent. Results: Most patients included in this study were asymptomatic, with this pathology being more common in patients over 60 years of age, and more common in women. The occurrence of malignant PSFT in our study was 17.77% (8 cases). All cases were submitted to surgery with curative intent, with a single case developing further recurrence. In order to achieve complete resection en bloc resection of the tumor with the chest wall, resection was performed in two cases, while lower lobectomy, pneumectomy, and hemidiaphragm resection, respectively, were needed in each case. Postoperative mortality was null. Conclusion: Thoracic CT scan remains the most important imagistic investigation in diagnosing. MRI is superior to thoracic CT, especially in cases that involved the larger blood vessels within the thorax, spinal column, or diaphragm. Complete surgical resection is the gold standard in treatment of PSFT, and the prognosis in benign cases is very good. MDPI 2020-04-16 /pmc/articles/PMC7230748/ /pubmed/32316178 http://dx.doi.org/10.3390/medicina56040185 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Savu, Cornel Melinte, Alexandru Posea, Radu Galie, Niculae Balescu, Irina Diaconu, Camelia Cretoiu, Dragos Dima, Simona Filipescu, Alexandru Balalau, Cristian Bacalbasa, Nicolae Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients |
title | Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients |
title_full | Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients |
title_fullStr | Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients |
title_full_unstemmed | Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients |
title_short | Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients |
title_sort | pleural solitary fibrous tumors—a retrospective study on 45 patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230748/ https://www.ncbi.nlm.nih.gov/pubmed/32316178 http://dx.doi.org/10.3390/medicina56040185 |
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