Cargando…

Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients

Introduction: The purpose of this paper is to study the type, the clinical presentation, and the best diagnostic methods for pleural solitary fibrous tumors (PSFTs), as well as to evaluate which is the most appropriate treatment, especially as PSFTs represent a rare occurrence in the thoracic pathol...

Descripción completa

Detalles Bibliográficos
Autores principales: Savu, Cornel, Melinte, Alexandru, Posea, Radu, Galie, Niculae, Balescu, Irina, Diaconu, Camelia, Cretoiu, Dragos, Dima, Simona, Filipescu, Alexandru, Balalau, Cristian, Bacalbasa, Nicolae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230748/
https://www.ncbi.nlm.nih.gov/pubmed/32316178
http://dx.doi.org/10.3390/medicina56040185
_version_ 1783535028276297728
author Savu, Cornel
Melinte, Alexandru
Posea, Radu
Galie, Niculae
Balescu, Irina
Diaconu, Camelia
Cretoiu, Dragos
Dima, Simona
Filipescu, Alexandru
Balalau, Cristian
Bacalbasa, Nicolae
author_facet Savu, Cornel
Melinte, Alexandru
Posea, Radu
Galie, Niculae
Balescu, Irina
Diaconu, Camelia
Cretoiu, Dragos
Dima, Simona
Filipescu, Alexandru
Balalau, Cristian
Bacalbasa, Nicolae
author_sort Savu, Cornel
collection PubMed
description Introduction: The purpose of this paper is to study the type, the clinical presentation, and the best diagnostic methods for pleural solitary fibrous tumors (PSFTs), as well as to evaluate which is the most appropriate treatment, especially as PSFTs represent a rare occurrence in the thoracic pathology. Material and Method: A retrospective study was conducted on a group of 45 patients submitted to surgery between January 2015 and December 2019. In most cases, the diagnosis was established through imaging studies—thoracic computed tomography (CT) scan with or without contrast—but also using magnetic resonance imaging (MRI) or positron emission tomography (PET) scans when data from CT scans were scarce. All patients were submitted to surgery with curative intent. Results: Most patients included in this study were asymptomatic, with this pathology being more common in patients over 60 years of age, and more common in women. The occurrence of malignant PSFT in our study was 17.77% (8 cases). All cases were submitted to surgery with curative intent, with a single case developing further recurrence. In order to achieve complete resection en bloc resection of the tumor with the chest wall, resection was performed in two cases, while lower lobectomy, pneumectomy, and hemidiaphragm resection, respectively, were needed in each case. Postoperative mortality was null. Conclusion: Thoracic CT scan remains the most important imagistic investigation in diagnosing. MRI is superior to thoracic CT, especially in cases that involved the larger blood vessels within the thorax, spinal column, or diaphragm. Complete surgical resection is the gold standard in treatment of PSFT, and the prognosis in benign cases is very good.
format Online
Article
Text
id pubmed-7230748
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-72307482020-05-22 Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients Savu, Cornel Melinte, Alexandru Posea, Radu Galie, Niculae Balescu, Irina Diaconu, Camelia Cretoiu, Dragos Dima, Simona Filipescu, Alexandru Balalau, Cristian Bacalbasa, Nicolae Medicina (Kaunas) Article Introduction: The purpose of this paper is to study the type, the clinical presentation, and the best diagnostic methods for pleural solitary fibrous tumors (PSFTs), as well as to evaluate which is the most appropriate treatment, especially as PSFTs represent a rare occurrence in the thoracic pathology. Material and Method: A retrospective study was conducted on a group of 45 patients submitted to surgery between January 2015 and December 2019. In most cases, the diagnosis was established through imaging studies—thoracic computed tomography (CT) scan with or without contrast—but also using magnetic resonance imaging (MRI) or positron emission tomography (PET) scans when data from CT scans were scarce. All patients were submitted to surgery with curative intent. Results: Most patients included in this study were asymptomatic, with this pathology being more common in patients over 60 years of age, and more common in women. The occurrence of malignant PSFT in our study was 17.77% (8 cases). All cases were submitted to surgery with curative intent, with a single case developing further recurrence. In order to achieve complete resection en bloc resection of the tumor with the chest wall, resection was performed in two cases, while lower lobectomy, pneumectomy, and hemidiaphragm resection, respectively, were needed in each case. Postoperative mortality was null. Conclusion: Thoracic CT scan remains the most important imagistic investigation in diagnosing. MRI is superior to thoracic CT, especially in cases that involved the larger blood vessels within the thorax, spinal column, or diaphragm. Complete surgical resection is the gold standard in treatment of PSFT, and the prognosis in benign cases is very good. MDPI 2020-04-16 /pmc/articles/PMC7230748/ /pubmed/32316178 http://dx.doi.org/10.3390/medicina56040185 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Savu, Cornel
Melinte, Alexandru
Posea, Radu
Galie, Niculae
Balescu, Irina
Diaconu, Camelia
Cretoiu, Dragos
Dima, Simona
Filipescu, Alexandru
Balalau, Cristian
Bacalbasa, Nicolae
Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients
title Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients
title_full Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients
title_fullStr Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients
title_full_unstemmed Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients
title_short Pleural Solitary Fibrous Tumors—A Retrospective Study on 45 Patients
title_sort pleural solitary fibrous tumors—a retrospective study on 45 patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230748/
https://www.ncbi.nlm.nih.gov/pubmed/32316178
http://dx.doi.org/10.3390/medicina56040185
work_keys_str_mv AT savucornel pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT melintealexandru pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT posearadu pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT galieniculae pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT balescuirina pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT diaconucamelia pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT cretoiudragos pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT dimasimona pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT filipescualexandru pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT balalaucristian pleuralsolitaryfibroustumorsaretrospectivestudyon45patients
AT bacalbasanicolae pleuralsolitaryfibroustumorsaretrospectivestudyon45patients