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Amelioration of High-Insulin-Induced Skeletal Muscle Cell Insulin Resistance by Resveratrol Is Linked to Activation of AMPK and Restoration of GLUT4 Translocation

Insulin resistance, the hallmark of type 2 diabetes mellitus (T2DM), is linked to hyperinsulinemia, which develops to counterbalance initial peripheral hormone resistance. Studies indicate that chronically elevated levels of insulin lead to skeletal muscle insulin resistance by deregulating steps wi...

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Detalles Bibliográficos
Autores principales: Vlavcheski, Filip, Den Hartogh, Danja J., Giacca, Adria, Tsiani, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230755/
https://www.ncbi.nlm.nih.gov/pubmed/32230718
http://dx.doi.org/10.3390/nu12040914