A Novel High-Throughput Screening Platform Identifies Itaconate Derivatives from Marine Penicillium antarcticum as Inhibitors of Mesenchymal Stem Cell Differentiation

Worldwide diffused diseases such as osteoarthritis, atherosclerosis or chronic kidney disease are associated with a tissue calcification process which may involve unexpected local stem cell differentiation. Current pharmacological treatments for such musculoskeletal conditions are weakly effective,...

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Detalles Bibliográficos
Autores principales: Marchese, Pietro, Mahajan, Nipun, O’Connell, Enda, Fearnhead, Howard, Tuohy, Maria, Krawczyk, Janusz, Thomas, Olivier P., Barry, Frank, Murphy, Mary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230868/
https://www.ncbi.nlm.nih.gov/pubmed/32260516
http://dx.doi.org/10.3390/md18040192

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