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Impact of the Geriatric Nutritional Risk Index on In-Hospital Mortality and Length of Hospitalization in Patients with Acute Decompensated Heart Failure with Preserved or Reduced Ejection Fraction

In patients with heart failure (HF), the impact of the Geriatric Nutritional Risk Index (GNRI) on in-hospital mortality and length of hospital stay remains unclear. We aimed to identify the factors associated with increased in-hospital mortality and longer length of hospital stay considering the GNR...

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Autores principales: Hirose, Susumu, Miyazaki, Sakiko, Yatsu, Shoichiro, Sato, Akihiro, Ishiwata, Sayaki, Matsumoto, Hiroki, Shitara, Jun, Murata, Azusa, Kato, Takao, Suda, Shoko, Matsue, Yuya, Hiki, Masaru, Takagi, Atsutoshi, Daida, Hiroyuki, Kasai, Takatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231029/
https://www.ncbi.nlm.nih.gov/pubmed/32325805
http://dx.doi.org/10.3390/jcm9041169
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author Hirose, Susumu
Miyazaki, Sakiko
Yatsu, Shoichiro
Sato, Akihiro
Ishiwata, Sayaki
Matsumoto, Hiroki
Shitara, Jun
Murata, Azusa
Kato, Takao
Suda, Shoko
Matsue, Yuya
Hiki, Masaru
Takagi, Atsutoshi
Daida, Hiroyuki
Kasai, Takatoshi
author_facet Hirose, Susumu
Miyazaki, Sakiko
Yatsu, Shoichiro
Sato, Akihiro
Ishiwata, Sayaki
Matsumoto, Hiroki
Shitara, Jun
Murata, Azusa
Kato, Takao
Suda, Shoko
Matsue, Yuya
Hiki, Masaru
Takagi, Atsutoshi
Daida, Hiroyuki
Kasai, Takatoshi
author_sort Hirose, Susumu
collection PubMed
description In patients with heart failure (HF), the impact of the Geriatric Nutritional Risk Index (GNRI) on in-hospital mortality and length of hospital stay remains unclear. We aimed to identify the factors associated with increased in-hospital mortality and longer length of hospital stay considering the GNRI in acute decompensated HF with reduced and preserved ejection fraction (HFrEF and HFpEF, respectively). Patients with acute decompensated HF who were admitted to our institution between 2007 and 2011 were investigated. A total of 451 (201, HFrEF; 250, HFpEF) patients were divided into the following: patients with GNRI < 92 and ≥92. In HFrEF, there were no significant differences in in-hospital mortality and length of hospital stay between patients with GNRI < 92 and ≥92 (median (interquartile range), 24.0 (23.8) days and 20.0 (15.0) days, respectively, p = 0.32). In HFpEF, despite no differences in in-hospital mortality, patients with GNRI < 92 had significantly longer length of hospital stay than those with GNRI ≥ 92 (median (interquartile range), 20.0 (22.3) days and 17.0 (16.0) days, respectively, p = 0.04). In HFpEF, GNRI < 92, along with lower hemoglobin, higher B-type natriuretic peptide, and elevated C-reactive protein levels, were the independent factors for longer length of hospital stay. Among patients with acute decompensated HF, assessment of nutritional status with GNRI is useful for stratifying patients at high risk for longer length of hospital stay in HFpEF but not in HFrEF. These observations are particularly important when considering the increasing elderly population and prevalence of HFpEF.
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spelling pubmed-72310292020-05-22 Impact of the Geriatric Nutritional Risk Index on In-Hospital Mortality and Length of Hospitalization in Patients with Acute Decompensated Heart Failure with Preserved or Reduced Ejection Fraction Hirose, Susumu Miyazaki, Sakiko Yatsu, Shoichiro Sato, Akihiro Ishiwata, Sayaki Matsumoto, Hiroki Shitara, Jun Murata, Azusa Kato, Takao Suda, Shoko Matsue, Yuya Hiki, Masaru Takagi, Atsutoshi Daida, Hiroyuki Kasai, Takatoshi J Clin Med Article In patients with heart failure (HF), the impact of the Geriatric Nutritional Risk Index (GNRI) on in-hospital mortality and length of hospital stay remains unclear. We aimed to identify the factors associated with increased in-hospital mortality and longer length of hospital stay considering the GNRI in acute decompensated HF with reduced and preserved ejection fraction (HFrEF and HFpEF, respectively). Patients with acute decompensated HF who were admitted to our institution between 2007 and 2011 were investigated. A total of 451 (201, HFrEF; 250, HFpEF) patients were divided into the following: patients with GNRI < 92 and ≥92. In HFrEF, there were no significant differences in in-hospital mortality and length of hospital stay between patients with GNRI < 92 and ≥92 (median (interquartile range), 24.0 (23.8) days and 20.0 (15.0) days, respectively, p = 0.32). In HFpEF, despite no differences in in-hospital mortality, patients with GNRI < 92 had significantly longer length of hospital stay than those with GNRI ≥ 92 (median (interquartile range), 20.0 (22.3) days and 17.0 (16.0) days, respectively, p = 0.04). In HFpEF, GNRI < 92, along with lower hemoglobin, higher B-type natriuretic peptide, and elevated C-reactive protein levels, were the independent factors for longer length of hospital stay. Among patients with acute decompensated HF, assessment of nutritional status with GNRI is useful for stratifying patients at high risk for longer length of hospital stay in HFpEF but not in HFrEF. These observations are particularly important when considering the increasing elderly population and prevalence of HFpEF. MDPI 2020-04-19 /pmc/articles/PMC7231029/ /pubmed/32325805 http://dx.doi.org/10.3390/jcm9041169 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hirose, Susumu
Miyazaki, Sakiko
Yatsu, Shoichiro
Sato, Akihiro
Ishiwata, Sayaki
Matsumoto, Hiroki
Shitara, Jun
Murata, Azusa
Kato, Takao
Suda, Shoko
Matsue, Yuya
Hiki, Masaru
Takagi, Atsutoshi
Daida, Hiroyuki
Kasai, Takatoshi
Impact of the Geriatric Nutritional Risk Index on In-Hospital Mortality and Length of Hospitalization in Patients with Acute Decompensated Heart Failure with Preserved or Reduced Ejection Fraction
title Impact of the Geriatric Nutritional Risk Index on In-Hospital Mortality and Length of Hospitalization in Patients with Acute Decompensated Heart Failure with Preserved or Reduced Ejection Fraction
title_full Impact of the Geriatric Nutritional Risk Index on In-Hospital Mortality and Length of Hospitalization in Patients with Acute Decompensated Heart Failure with Preserved or Reduced Ejection Fraction
title_fullStr Impact of the Geriatric Nutritional Risk Index on In-Hospital Mortality and Length of Hospitalization in Patients with Acute Decompensated Heart Failure with Preserved or Reduced Ejection Fraction
title_full_unstemmed Impact of the Geriatric Nutritional Risk Index on In-Hospital Mortality and Length of Hospitalization in Patients with Acute Decompensated Heart Failure with Preserved or Reduced Ejection Fraction
title_short Impact of the Geriatric Nutritional Risk Index on In-Hospital Mortality and Length of Hospitalization in Patients with Acute Decompensated Heart Failure with Preserved or Reduced Ejection Fraction
title_sort impact of the geriatric nutritional risk index on in-hospital mortality and length of hospitalization in patients with acute decompensated heart failure with preserved or reduced ejection fraction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231029/
https://www.ncbi.nlm.nih.gov/pubmed/32325805
http://dx.doi.org/10.3390/jcm9041169
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