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The Association between Serum Levels of 25[OH]D, Body Weight Changes and Body Composition Indices in Patients with Heart Failure

We try to determine the association between weight changes (WC), both loss or gain, body composition indices (BCI) and serum levels of 25[OH]D during heart failure (HF). WC was determined in 412 patients (14.3% female, aged: 53.6 ± 10.0 years, NYHA class: 2.5 ± 0.8). Body fat, fat percentage and fat...

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Autores principales: Stefaniak, Apolonia, Partyka, Robert, Duda, Sylwia, Ostręga, Weronika, Niedziela, Jacek, Nowak, Jolanta, Malinowska-Borowska, Jolanta, Rywik, Tomasz, Leszek, Przemysław, Hudzik, Bartosz, Zubelewicz-Szkodzińska, Barbara, Rozentryt, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231116/
https://www.ncbi.nlm.nih.gov/pubmed/32344712
http://dx.doi.org/10.3390/jcm9041228
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author Stefaniak, Apolonia
Partyka, Robert
Duda, Sylwia
Ostręga, Weronika
Niedziela, Jacek
Nowak, Jolanta
Malinowska-Borowska, Jolanta
Rywik, Tomasz
Leszek, Przemysław
Hudzik, Bartosz
Zubelewicz-Szkodzińska, Barbara
Rozentryt, Piotr
author_facet Stefaniak, Apolonia
Partyka, Robert
Duda, Sylwia
Ostręga, Weronika
Niedziela, Jacek
Nowak, Jolanta
Malinowska-Borowska, Jolanta
Rywik, Tomasz
Leszek, Przemysław
Hudzik, Bartosz
Zubelewicz-Szkodzińska, Barbara
Rozentryt, Piotr
author_sort Stefaniak, Apolonia
collection PubMed
description We try to determine the association between weight changes (WC), both loss or gain, body composition indices (BCI) and serum levels of 25[OH]D during heart failure (HF). WC was determined in 412 patients (14.3% female, aged: 53.6 ± 10.0 years, NYHA class: 2.5 ± 0.8). Body fat, fat percentage and fat-free mass determined by dual energy X-rays absorptiometry (DEXA) and serum levels of 25[OH]D were analyzed. Logistic regression was used to calculate odds ratios for 25[OH]D insufficiency (<30 ng/mL) or deficiency (<20 ng/mL) by quintiles of WC, in comparison to weight-stable subgroup. The serum 25[OH]D was lower in weight loosing than weight stable subgroup. In fully adjusted models the risk of either insufficient or deficient 25[OH]D levels was independent of BCI and HF severity markers. The risk was elevated in higher weight loss subgroups but also in weight gain subgroup. In full adjustment, the odds for 25[OH]D deficiency in the top weight loss and weight gain subgroups were 3.30; 95%CI: 1.37–7.93, p = 0.008 and 2.41; 95%CI: 0.91–6.38, p = 0.08, respectively. The risk of 25[OH]D deficiency/insufficiency was also independently associated with potential UVB exposure, but not with nutritional status and BCI. Metabolic instability in HF was reflected by edema-free WC, but not nutritional status. BCI is independently associated with deficiency/insufficiency of serum 25[OH]D.
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spelling pubmed-72311162020-05-22 The Association between Serum Levels of 25[OH]D, Body Weight Changes and Body Composition Indices in Patients with Heart Failure Stefaniak, Apolonia Partyka, Robert Duda, Sylwia Ostręga, Weronika Niedziela, Jacek Nowak, Jolanta Malinowska-Borowska, Jolanta Rywik, Tomasz Leszek, Przemysław Hudzik, Bartosz Zubelewicz-Szkodzińska, Barbara Rozentryt, Piotr J Clin Med Article We try to determine the association between weight changes (WC), both loss or gain, body composition indices (BCI) and serum levels of 25[OH]D during heart failure (HF). WC was determined in 412 patients (14.3% female, aged: 53.6 ± 10.0 years, NYHA class: 2.5 ± 0.8). Body fat, fat percentage and fat-free mass determined by dual energy X-rays absorptiometry (DEXA) and serum levels of 25[OH]D were analyzed. Logistic regression was used to calculate odds ratios for 25[OH]D insufficiency (<30 ng/mL) or deficiency (<20 ng/mL) by quintiles of WC, in comparison to weight-stable subgroup. The serum 25[OH]D was lower in weight loosing than weight stable subgroup. In fully adjusted models the risk of either insufficient or deficient 25[OH]D levels was independent of BCI and HF severity markers. The risk was elevated in higher weight loss subgroups but also in weight gain subgroup. In full adjustment, the odds for 25[OH]D deficiency in the top weight loss and weight gain subgroups were 3.30; 95%CI: 1.37–7.93, p = 0.008 and 2.41; 95%CI: 0.91–6.38, p = 0.08, respectively. The risk of 25[OH]D deficiency/insufficiency was also independently associated with potential UVB exposure, but not with nutritional status and BCI. Metabolic instability in HF was reflected by edema-free WC, but not nutritional status. BCI is independently associated with deficiency/insufficiency of serum 25[OH]D. MDPI 2020-04-24 /pmc/articles/PMC7231116/ /pubmed/32344712 http://dx.doi.org/10.3390/jcm9041228 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Stefaniak, Apolonia
Partyka, Robert
Duda, Sylwia
Ostręga, Weronika
Niedziela, Jacek
Nowak, Jolanta
Malinowska-Borowska, Jolanta
Rywik, Tomasz
Leszek, Przemysław
Hudzik, Bartosz
Zubelewicz-Szkodzińska, Barbara
Rozentryt, Piotr
The Association between Serum Levels of 25[OH]D, Body Weight Changes and Body Composition Indices in Patients with Heart Failure
title The Association between Serum Levels of 25[OH]D, Body Weight Changes and Body Composition Indices in Patients with Heart Failure
title_full The Association between Serum Levels of 25[OH]D, Body Weight Changes and Body Composition Indices in Patients with Heart Failure
title_fullStr The Association between Serum Levels of 25[OH]D, Body Weight Changes and Body Composition Indices in Patients with Heart Failure
title_full_unstemmed The Association between Serum Levels of 25[OH]D, Body Weight Changes and Body Composition Indices in Patients with Heart Failure
title_short The Association between Serum Levels of 25[OH]D, Body Weight Changes and Body Composition Indices in Patients with Heart Failure
title_sort association between serum levels of 25[oh]d, body weight changes and body composition indices in patients with heart failure
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231116/
https://www.ncbi.nlm.nih.gov/pubmed/32344712
http://dx.doi.org/10.3390/jcm9041228
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