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Establishment of a Recombinant AAV2/HBoV1 Vector Production System in Insect Cells

We have previously developed an rAAV2/HBoV1 vector in which a recombinant adeno-associated virus 2 (rAAV2) genome is pseudopackaged into a human bocavirus 1 (HBoV1) capsid. Recently, the production of rAAV2/HBoV1 in human embryonic kidney (HEK) 293 cells has been greatly improved in the absence of a...

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Detalles Bibliográficos
Autores principales: Deng, Xuefeng, Zou, Wei, Yan, Ziying, Qiu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231168/
https://www.ncbi.nlm.nih.gov/pubmed/32316599
http://dx.doi.org/10.3390/genes11040439