The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis

Medium-chain fatty acids (MCFAs) have been associated with anti-steatotic effects in hepatocytes. Expression of the MCFA receptor GPR84 (G protein-coupled receptor 84) is induced in immune cells under inflammatory conditions and can promote fibrogenesis. We aimed at deciphering the role of GPR84 in...

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Detalles Bibliográficos
Autores principales: Puengel, Tobias, De Vos, Steve, Hundertmark, Jana, Kohlhepp, Marlene, Guldiken, Nurdan, Pujuguet, Philippe, Auberval, Marielle, Marsais, Florence, Shoji, Kenji F., Saniere, Laurent, Trautwein, Christian, Luedde, Tom, Strnad, Pavel, Brys, Reginald, Clément-Lacroix, Philippe, Tacke, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231190/
https://www.ncbi.nlm.nih.gov/pubmed/32316235
http://dx.doi.org/10.3390/jcm9041140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231190/
https://www.ncbi.nlm.nih.gov/pubmed/32316235
http://dx.doi.org/10.3390/jcm9041140

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