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TWINKLE and Other Human Mitochondrial DNA Helicases: Structure, Function and Disease
Mammalian mitochondria contain a circular genome (mtDNA) which encodes subunits of the oxidative phosphorylation machinery. The replication and maintenance of mtDNA is carried out by a set of nuclear-encoded factors—of which, helicases form an important group. The TWINKLE helicase is the main helica...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231222/ https://www.ncbi.nlm.nih.gov/pubmed/32283748 http://dx.doi.org/10.3390/genes11040408 |