Cargando…

Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species

In Korea, various insect species such as crickets and grasshoppers, as well as honey bee and silkworm pupae, have been consumed as food and used in oriental medicine. In this study to evaluate useful the bioactivities and potentially adverse effects of edible insects, ethanol extracts of Allomyrina...

Descripción completa

Detalles Bibliográficos
Autores principales: Pyo, Su-Jin, Kang, Deok-Gyeong, Jung, Chuleui, Sohn, Ho-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231258/
https://www.ncbi.nlm.nih.gov/pubmed/32244589
http://dx.doi.org/10.3390/foods9040401
_version_ 1783535149803110400
author Pyo, Su-Jin
Kang, Deok-Gyeong
Jung, Chuleui
Sohn, Ho-Yong
author_facet Pyo, Su-Jin
Kang, Deok-Gyeong
Jung, Chuleui
Sohn, Ho-Yong
author_sort Pyo, Su-Jin
collection PubMed
description In Korea, various insect species such as crickets and grasshoppers, as well as honey bee and silkworm pupae, have been consumed as food and used in oriental medicine. In this study to evaluate useful the bioactivities and potentially adverse effects of edible insects, ethanol extracts of Allomyrina dichotoma (AD), Tenebrio molitor (TM), Protaetia brevitarsis (PB), Gryllus bimaculatus (GB), Teleogryllus emma (TE), and Apis mellifera (AM) were prepared and evaluated with regard to their anti-thrombosis, anti-oxidant and haemolysis activities against human red blood cells. AD and TE extracts showed strong anti-oxidant activities, which were not related to polyphenol content. All ethanol extracts, except AM extract, showed strong platelet aggregation activities. The platelet aggregation ratios of the extracts were 194%–246% of those of the solvent controls. The effects of the AD, TM, PB, GM, and AM extracts on thrombin, prothrombin and various coagulation factors were negligible. Only the extract of TM showed concentration-dependent anti-coagulation activities, with a 1.75-fold aPTT (activated Partial Thromboplastin Time) extension at 5 mg/mL. Of the six insect extracts, TM and AM extracts exhibited potent haemolytic activity. Our results on the insect extracts’ functional properties suggest that edible insects have considerable potential not just as a food source but as a novel bio-resource as well.
format Online
Article
Text
id pubmed-7231258
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-72312582020-05-22 Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species Pyo, Su-Jin Kang, Deok-Gyeong Jung, Chuleui Sohn, Ho-Yong Foods Article In Korea, various insect species such as crickets and grasshoppers, as well as honey bee and silkworm pupae, have been consumed as food and used in oriental medicine. In this study to evaluate useful the bioactivities and potentially adverse effects of edible insects, ethanol extracts of Allomyrina dichotoma (AD), Tenebrio molitor (TM), Protaetia brevitarsis (PB), Gryllus bimaculatus (GB), Teleogryllus emma (TE), and Apis mellifera (AM) were prepared and evaluated with regard to their anti-thrombosis, anti-oxidant and haemolysis activities against human red blood cells. AD and TE extracts showed strong anti-oxidant activities, which were not related to polyphenol content. All ethanol extracts, except AM extract, showed strong platelet aggregation activities. The platelet aggregation ratios of the extracts were 194%–246% of those of the solvent controls. The effects of the AD, TM, PB, GM, and AM extracts on thrombin, prothrombin and various coagulation factors were negligible. Only the extract of TM showed concentration-dependent anti-coagulation activities, with a 1.75-fold aPTT (activated Partial Thromboplastin Time) extension at 5 mg/mL. Of the six insect extracts, TM and AM extracts exhibited potent haemolytic activity. Our results on the insect extracts’ functional properties suggest that edible insects have considerable potential not just as a food source but as a novel bio-resource as well. MDPI 2020-04-01 /pmc/articles/PMC7231258/ /pubmed/32244589 http://dx.doi.org/10.3390/foods9040401 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pyo, Su-Jin
Kang, Deok-Gyeong
Jung, Chuleui
Sohn, Ho-Yong
Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species
title Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species
title_full Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species
title_fullStr Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species
title_full_unstemmed Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species
title_short Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species
title_sort anti-thrombotic, anti-oxidant and haemolysis activities of six edible insect species
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231258/
https://www.ncbi.nlm.nih.gov/pubmed/32244589
http://dx.doi.org/10.3390/foods9040401
work_keys_str_mv AT pyosujin antithromboticantioxidantandhaemolysisactivitiesofsixedibleinsectspecies
AT kangdeokgyeong antithromboticantioxidantandhaemolysisactivitiesofsixedibleinsectspecies
AT jungchuleui antithromboticantioxidantandhaemolysisactivitiesofsixedibleinsectspecies
AT sohnhoyong antithromboticantioxidantandhaemolysisactivitiesofsixedibleinsectspecies