Cargando…
Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species
In Korea, various insect species such as crickets and grasshoppers, as well as honey bee and silkworm pupae, have been consumed as food and used in oriental medicine. In this study to evaluate useful the bioactivities and potentially adverse effects of edible insects, ethanol extracts of Allomyrina...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231258/ https://www.ncbi.nlm.nih.gov/pubmed/32244589 http://dx.doi.org/10.3390/foods9040401 |
_version_ | 1783535149803110400 |
---|---|
author | Pyo, Su-Jin Kang, Deok-Gyeong Jung, Chuleui Sohn, Ho-Yong |
author_facet | Pyo, Su-Jin Kang, Deok-Gyeong Jung, Chuleui Sohn, Ho-Yong |
author_sort | Pyo, Su-Jin |
collection | PubMed |
description | In Korea, various insect species such as crickets and grasshoppers, as well as honey bee and silkworm pupae, have been consumed as food and used in oriental medicine. In this study to evaluate useful the bioactivities and potentially adverse effects of edible insects, ethanol extracts of Allomyrina dichotoma (AD), Tenebrio molitor (TM), Protaetia brevitarsis (PB), Gryllus bimaculatus (GB), Teleogryllus emma (TE), and Apis mellifera (AM) were prepared and evaluated with regard to their anti-thrombosis, anti-oxidant and haemolysis activities against human red blood cells. AD and TE extracts showed strong anti-oxidant activities, which were not related to polyphenol content. All ethanol extracts, except AM extract, showed strong platelet aggregation activities. The platelet aggregation ratios of the extracts were 194%–246% of those of the solvent controls. The effects of the AD, TM, PB, GM, and AM extracts on thrombin, prothrombin and various coagulation factors were negligible. Only the extract of TM showed concentration-dependent anti-coagulation activities, with a 1.75-fold aPTT (activated Partial Thromboplastin Time) extension at 5 mg/mL. Of the six insect extracts, TM and AM extracts exhibited potent haemolytic activity. Our results on the insect extracts’ functional properties suggest that edible insects have considerable potential not just as a food source but as a novel bio-resource as well. |
format | Online Article Text |
id | pubmed-7231258 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72312582020-05-22 Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species Pyo, Su-Jin Kang, Deok-Gyeong Jung, Chuleui Sohn, Ho-Yong Foods Article In Korea, various insect species such as crickets and grasshoppers, as well as honey bee and silkworm pupae, have been consumed as food and used in oriental medicine. In this study to evaluate useful the bioactivities and potentially adverse effects of edible insects, ethanol extracts of Allomyrina dichotoma (AD), Tenebrio molitor (TM), Protaetia brevitarsis (PB), Gryllus bimaculatus (GB), Teleogryllus emma (TE), and Apis mellifera (AM) were prepared and evaluated with regard to their anti-thrombosis, anti-oxidant and haemolysis activities against human red blood cells. AD and TE extracts showed strong anti-oxidant activities, which were not related to polyphenol content. All ethanol extracts, except AM extract, showed strong platelet aggregation activities. The platelet aggregation ratios of the extracts were 194%–246% of those of the solvent controls. The effects of the AD, TM, PB, GM, and AM extracts on thrombin, prothrombin and various coagulation factors were negligible. Only the extract of TM showed concentration-dependent anti-coagulation activities, with a 1.75-fold aPTT (activated Partial Thromboplastin Time) extension at 5 mg/mL. Of the six insect extracts, TM and AM extracts exhibited potent haemolytic activity. Our results on the insect extracts’ functional properties suggest that edible insects have considerable potential not just as a food source but as a novel bio-resource as well. MDPI 2020-04-01 /pmc/articles/PMC7231258/ /pubmed/32244589 http://dx.doi.org/10.3390/foods9040401 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pyo, Su-Jin Kang, Deok-Gyeong Jung, Chuleui Sohn, Ho-Yong Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species |
title | Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species |
title_full | Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species |
title_fullStr | Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species |
title_full_unstemmed | Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species |
title_short | Anti-Thrombotic, Anti-Oxidant and Haemolysis Activities of Six Edible Insect Species |
title_sort | anti-thrombotic, anti-oxidant and haemolysis activities of six edible insect species |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231258/ https://www.ncbi.nlm.nih.gov/pubmed/32244589 http://dx.doi.org/10.3390/foods9040401 |
work_keys_str_mv | AT pyosujin antithromboticantioxidantandhaemolysisactivitiesofsixedibleinsectspecies AT kangdeokgyeong antithromboticantioxidantandhaemolysisactivitiesofsixedibleinsectspecies AT jungchuleui antithromboticantioxidantandhaemolysisactivitiesofsixedibleinsectspecies AT sohnhoyong antithromboticantioxidantandhaemolysisactivitiesofsixedibleinsectspecies |