Cargando…
In Situ Gel Loaded with Chitosan-Coated Simvastatin Nanoparticles: Promising Delivery for Effective Anti-Proliferative Activity against Tongue Carcinoma
The goal of this study is to develop optimized chitosan-coated Simvastatin (SIM) nanoparticles (NPs) loaded in an in situ gel (ISG) formulation via a face-centered central composite design (FCCCD). Coated SIM-NPs were doped with Quercetin (QRC) using a modified nanoprecipitation method. The concentr...
Autores principales: | Kurakula, Mallesh, Naveen, N. Raghavendra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231276/ https://www.ncbi.nlm.nih.gov/pubmed/32283782 http://dx.doi.org/10.3390/md18040201 |
Ejemplares similares
-
QbD Supported Optimization of the Alginate-Chitosan Nanoparticles of Simvastatin in Enhancing the Anti-Proliferative Activity against Tongue Carcinoma
por: Rizg, Waleed Y., et al.
Publicado: (2022) -
Chitosan Coated Microparticles Enhance Simvastatin Colon Targeting and Pro-Apoptotic Activity
por: Alhakamy, Nabil A., et al.
Publicado: (2020) -
Preparation, Optimization and Evaluation of Chitosan-Based Avanafil Nanocomplex Utilizing Antioxidants for Enhanced Neuroprotective Effect on PC12 Cells
por: Kurakula, Mallesh, et al.
Publicado: (2021) -
Response Surface Methodology (RSM) Powered Formulation Development, Optimization and Evaluation of Thiolated Based Mucoadhesive Nanocrystals for Local Delivery of Simvastatin
por: Bakhaidar, Rana B., et al.
Publicado: (2022) -
Thermoreversible in situ gel for subgingival delivery of simvastatin for treatment of periodontal disease
por: Rajendran, Swaminathan, et al.
Publicado: (2017)