Nitric Oxide Stimulates Acute Pancreatitis Pain via Activating the NF-κB Signaling Pathway and Inhibiting the Kappa Opioid Receptor

Pain is the most important clinical feature of acute pancreatitis (AP); however, its specific mechanism is currently unclear. In this study, we showed that AP caused an increase in nitric oxide (NO) secretion, activated the NF-κB pathway in the dorsal root ganglia (DRGs), and caused pain. We establi...

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Detalles Bibliográficos
Autores principales: Xue, Mengwen, Han, Liang, Qian, Weikun, Li, Jie, Qin, Tao, Xiao, Ying, Ma, Qingyong, Ma, Jiguang, Shen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231422/
https://www.ncbi.nlm.nih.gov/pubmed/32454946
http://dx.doi.org/10.1155/2020/9230958

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