Cargando…
Efficacy of novel immunotherapy regimens in patients with metastatic melanoma with germline CDKN2A mutations
BACKGROUND: Inherited CDKN2A mutation is a strong risk factor for cutaneous melanoma. Moreover, carriers have been found to have poor melanoma-specific survival. In this study, responses to novel immunotherapy agents in CDKN2A mutation carriers with metastatic melanoma were evaluated. METHODS: CDKN2...
Autores principales: | Helgadottir, Hildur, Ghiorzo, Paola, van Doorn, Remco, Puig, Susana, Levin, Max, Kefford, Richard, Lauss, Martin, Queirolo, Paola, Pastorino, Lorenza, Kapiteijn, Ellen, Potrony, Miriam, Carrera, Cristina, Olsson, Håkan, Höiom, Veronica, Jönsson, Göran |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231460/ https://www.ncbi.nlm.nih.gov/pubmed/30291219 http://dx.doi.org/10.1136/jmedgenet-2018-105610 |
Ejemplares similares
-
Efficacy of BRAF and MEK Inhibition in Patients with BRAF-Mutant Advanced Melanoma and Germline CDKN2A Pathogenic Variants
por: Spagnolo, Francesco, et al.
Publicado: (2021) -
High risk of tobacco-related cancers in CDKN2A mutation-positive melanoma families
por: Helgadottir, Hildur, et al.
Publicado: (2014) -
Functional analysis of a CDKN2A 5’UTR germline variant associated with pancreatic cancer development
por: Bruno, William, et al.
Publicado: (2017) -
The genetics of uveal melanoma: current insights
por: Helgadottir, Hildur, et al.
Publicado: (2016) -
Combining molecular and immunohistochemical analyses of key drivers in primary melanomas: interplay between germline and somatic variations
por: Bruno, William, et al.
Publicado: (2017)