In silico analysis of functional linkage among arsenic induced MATE genes in rice

MATE genes play an important role in cellular detoxification processes. Nine MATE genes were identified by a transcriptomics study previously. Candidate gene prioritization was done where 29 new genes were found to interact with 09 guide genes. Therefore, a total of 38 genes were analyzed here to pr...

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Detalles Bibliográficos
Autores principales: Seth, Snigdhamayee, Debnath, Sandip, Chakraborty, N.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231838/
https://www.ncbi.nlm.nih.gov/pubmed/32435604
http://dx.doi.org/10.1016/j.btre.2019.e00390
Descripción
Sumario:MATE genes play an important role in cellular detoxification processes. Nine MATE genes were identified by a transcriptomics study previously. Candidate gene prioritization was done where 29 new genes were found to interact with 09 guide genes. Therefore, a total of 38 genes were analyzed here to predict a concise model by gene prioritization study. Those genes were analyzed further in Rice Interactions Viewer programme, and based on high ICV, 10 new genes were found to interact among themselves at protein level. Surprisingly, only 05 genes were found to play a key role at protein level. These 15 genes were analyzed for their interaction with soil available inorganic arsenic species. Maximum expression levels were found mostly at young inflorescence and seed development stage for those genes. So, these genes may have a direct role in arsenic sequestration from cells and thereby providing safety to the developing embryo within the seed.

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