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A dual attack on the peroxide bond. The common principle of peroxidatic cysteine or selenocysteine residues

The (seleno)cysteine residues in some protein families react with hydroperoxides with rate constants far beyond those of fully dissociated low molecular weight thiol or selenol compounds. In case of the glutathione peroxidases, we could demonstrate that high rate constants are achieved by a proton t...

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Detalles Bibliográficos
Autores principales: Dalla Tiezza, M., Bickelhaupt, F.M., Flohé, L., Maiorino, M., Ursini, F., Orian, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231847/
https://www.ncbi.nlm.nih.gov/pubmed/32428845
http://dx.doi.org/10.1016/j.redox.2020.101540

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