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A dual attack on the peroxide bond. The common principle of peroxidatic cysteine or selenocysteine residues
The (seleno)cysteine residues in some protein families react with hydroperoxides with rate constants far beyond those of fully dissociated low molecular weight thiol or selenol compounds. In case of the glutathione peroxidases, we could demonstrate that high rate constants are achieved by a proton t...
Autores principales: | Dalla Tiezza, M., Bickelhaupt, F.M., Flohé, L., Maiorino, M., Ursini, F., Orian, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231847/ https://www.ncbi.nlm.nih.gov/pubmed/32428845 http://dx.doi.org/10.1016/j.redox.2020.101540 |
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