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Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells

Despite extensive mapping of long noncoding RNAs in immune cells, their function in vivo remains poorly understood. In this study, we identify over 100 long noncoding RNAs that are differentially expressed within 24 h of Th1 cell activation. Among those, we show that suppression of Malat1 is a hallm...

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Detalles Bibliográficos
Autores principales:	Hewitson, James P., West, Katie A., James, Kylie R., Rani, Gulab Fatima, Dey, Nidhi, Romano, Audrey, Brown, Najmeeyah, Teichmann, Sarah A., Kaye, Paul M., Lagos, Dimitris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2020
Materias:	Immune Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231852/ https://www.ncbi.nlm.nih.gov/pubmed/32321759 http://dx.doi.org/10.4049/jimmunol.1900940

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