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MK2206 Enhances Cisplatin-Induced Cytotoxicity and Apoptosis in Testicular Cancer Through Akt Signaling Pathway Inhibition

OBJECTIVE: To improve conventional chemotherapeutic efficacy, it is significant to identify novel molecular markers for chemosensitivity as well as possible molecules accelerating cell-killing mechanisms. In this study, we attempted to elucidate how MK2206, an allosteric Akt inhibitor, enhances the...

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Detalles Bibliográficos
Autores principales:	Sun, Dingqi, Wang, Jinhua, Zhang, Hui, Liu, Shuai, Wei, Peng, Wang, Haoran, Xu, Zhen, Fu, Qiang, Zhang, Keqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2020
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231864/ https://www.ncbi.nlm.nih.gov/pubmed/32422572 http://dx.doi.org/10.1016/j.tranon.2020.100769

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