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All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug Evaluation
High-throughput in vitro drug assays have been impacted by recent advances in human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) technology and by contact-free all-optical systems simultaneously measuring action potentials (APs) and Ca(2+) transients (CaTrs). Parallel computational...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231889/ https://www.ncbi.nlm.nih.gov/pubmed/32298635 http://dx.doi.org/10.1016/j.bpj.2020.03.018 |