Allopregnanolone: From molecular pathophysiology to therapeutics. A historical perspective

Allopregnanolone is synthesized in the central nervous system either de novo from cholesterol or from steroid hormone precursors like progesterone and pregnenolone. Over the past 30 years, direct and rapid, non-genomic actions of allopregnanolone and its derivatives via GABA(A) receptors have been d...

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Detalles Bibliográficos
Autores principales: Paul, Steven M, Pinna, Graziano, Guidotti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Articles from the Special Issue on Allopregnanolone role in the neurobiology of stress and mood disorders; Edited by Graziano Pinna
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231972/
https://www.ncbi.nlm.nih.gov/pubmed/32435665
http://dx.doi.org/10.1016/j.ynstr.2020.100215

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