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miRNA-98-5p Targeting IGF2BP1 Induces Mesenchymal Stem Cell Apoptosis by Modulating PI3K/Akt and p53 in Immune Thrombocytopenia

Immune thrombocytopenia (ITP) is a common hematological autoimmune disease, in which defective mesenchymal stem cells (MSCs) are potentially involved. Our previous study suggested that MSCs in ITP patients displayed enhanced apoptosis. MicroRNAs (miRNAs) play important roles in ITP by affecting mega...

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Detalles Bibliográficos
Autores principales: Wang, Yanan, Zhang, Jiamin, Su, Yan, Wang, Chencong, Zhang, Gaochao, Liu, Xiao, Chen, Qi, Lv, Meng, Chang, Yingjun, Peng, Jun, Hou, Ming, Huang, Xiaojun, Zhang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232042/
https://www.ncbi.nlm.nih.gov/pubmed/32428701
http://dx.doi.org/10.1016/j.omtn.2020.04.013