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Ramipril pretreatment worsened renal injury and survival despite a reduction in renal inflammation in experimentally induced sepsis in mice

INTRODUCTION: The angiotensin converting enzyme inhibitor ramipril is a standard antihypertensive therapy for many patients. Because angiotensin II may promote inflammation, we were interested in whether basal pretreatment with ramipril may modify renal function and inflammation as well as systemic...

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Detalles Bibliográficos
Autores principales: Bondeva, Tzvetanka, Schindler, Katrin, Schindler, Claudia, Wolf, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232051/
https://www.ncbi.nlm.nih.gov/pubmed/32419571
http://dx.doi.org/10.1177/1470320320923977