Tetraspanin CD53 Promotes Lymphocyte Recirculation by Stabilizing L-Selectin Surface Expression

Tetraspanins regulate key processes in immune cells; however, the function of the leukocyte-restricted tetraspanin CD53 is unknown. Here we show that CD53 is essential for lymphocyte recirculation. Lymph nodes of Cd53(−/−) mice were smaller than those of wild-type mice due to a marked reduction in B...

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Detalles Bibliográficos
Autores principales: Demaria, Maria C., Yeung, Louisa, Peeters, Rens, Wee, Janet L., Mihaljcic, Masa, Jones, Eleanor L., Nasa, Zeyad, Alderuccio, Frank, Hall, Pamela, Smith, Brodie C., Binger, Katrina J., Hammerling, Gunther, Kwok, Hang Fai, Newman, Andrew, Ager, Ann, van Spriel, Annemiek, Hickey, Michael J., Wright, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232089/
https://www.ncbi.nlm.nih.gov/pubmed/32428859
http://dx.doi.org/10.1016/j.isci.2020.101104

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