Type I Interferons Ameliorate Zinc Intoxication of Candida glabrata by Macrophages and Promote Fungal Immune Evasion

Host and fungal pathogens compete for metal ion acquisition during infectious processes, but molecular mechanisms remain largely unknown. Here, we show that type I interferons (IFNs-I) dysregulate zinc homeostasis in macrophages, which employ metallothionein-mediated zinc intoxication of pathogens a...

Descripción completa

Detalles Bibliográficos
Autores principales: Riedelberger, Michael, Penninger, Philipp, Tscherner, Michael, Hadriga, Bernhard, Brunnhofer, Carina, Jenull, Sabrina, Stoiber, Anton, Bourgeois, Christelle, Petryshyn, Andriy, Glaser, Walter, Limbeck, Andreas, Lynes, Michael A., Schabbauer, Gernot, Weiss, Guenter, Kuchler, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232100/
https://www.ncbi.nlm.nih.gov/pubmed/32428860
http://dx.doi.org/10.1016/j.isci.2020.101121

Ejemplares similares

Ejemplares similares