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Atorvastatin protects against postoperative neurocognitive disorder via a peroxisome proliferator-activated receptor-gamma signaling pathway in mice

OBJECTIVE: Postoperative neurocognitive disorder (PND) is a main complication that is commonly seen postoperatively in elderly patients. The underlying mechanism remains unclear, although neuroinflammation has been increasingly observed in PND. Atorvastatin is a pleiotropic agent with proven anti-in...

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Detalles Bibliográficos
Autores principales: Yang, Yinan, Wei, Changwei, Liu, Jinhu, Ma, Danxu, Xiong, Chao, Lin, Dandan, Wu, Anshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232118/
https://www.ncbi.nlm.nih.gov/pubmed/32412807
http://dx.doi.org/10.1177/0300060520924251