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IRF7 Is Required for the Second Phase Interferon Induction during Influenza Virus Infection in Human Lung Epithelia

Influenza A virus (IAV) infection is a major cause of morbidity and mortality. Retinoic acid-inducible protein I (RIG-I) plays an important role in the recognition of IAV in most cell types, and leads to the activation of interferon (IFN). We investigated mechanisms of RIG-I and IFN induction by IAV...

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Detalles Bibliográficos
Autores principales:	Wu, Wenxin, Zhang, Wei, Tian, Lili, Brown, Brent R., Walters, Matthew S., Metcalf, Jordan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232147/ https://www.ncbi.nlm.nih.gov/pubmed/32235406 http://dx.doi.org/10.3390/v12040377

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