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KSHV ORF59 and PAN RNA Recruit Histone Demethylases to the Viral Chromatin during Lytic Reactivation

Kaposi’s sarcoma-associated herpesvirus (KSHV) causes multiple malignancies in immunocompromised individuals. KSHV primarily establishes a lifelong latency in infected humans during which only a subset of viral genes is expressed while most of the viral genome remains transcriptionally silent with c...

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Detalles Bibliográficos
Autores principales: Hiura, Kayla, Strahan, Roxanne, Uppal, Timsy, Prince, Brian, Rossetto, Cyprian C., Verma, Subhash C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232192/
https://www.ncbi.nlm.nih.gov/pubmed/32283586
http://dx.doi.org/10.3390/v12040420