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The In Silico Prediction of Hotspot Residues that Contribute to the Structural Stability of Subunit Interfaces of a Picornavirus Capsid

The assembly of picornavirus capsids proceeds through the stepwise oligomerization of capsid protein subunits and depends on interactions between critical residues known as hotspots. Few studies have described the identification of hotspot residues at the protein subunit interfaces of the picornavir...

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Detalles Bibliográficos
Autores principales: Upfold, Nicole, Ross, Caroline, Tastan Bishop, Özlem, Knox, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232237/
https://www.ncbi.nlm.nih.gov/pubmed/32244486
http://dx.doi.org/10.3390/v12040387