Cargando…

Development and Application of Extraction Methods for LC-MS Quantification of Microcystins in Liver Tissue

A method was developed to extract and quantify microcystins (MCs) from mouse liver with limits of quantification (LOQs) lower than previously reported. MCs were extracted from 40-mg liver samples using 85:15 (v:v) CH(3)CN:H(2)O containing 200 mM ZnSO(4) and 1% formic acid. Solid-phase extraction wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baliu-Rodriguez, David, Kucheriavaia, Daria, Palagama, Dilrukshika S. W., Lad, Apurva, O’Neill, Grace M., Birbeck, Johnna A., Kennedy, David J., Haller, Steven T., Westrick, Judy A., Isailovic, Dragan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232250/ https://www.ncbi.nlm.nih.gov/pubmed/32325806 http://dx.doi.org/10.3390/toxins12040263

Ejemplares similares

Toward Revealing Microcystin Distribution in Mouse Liver Tissue Using MALDI-MS Imaging
por: Kucheriavaia, Daria, et al.
Publicado: (2021)

Comparative Analysis of Microcystin Prevalence in Michigan Lakes by Online Concentration LC/MS/MS and ELISA
por: Birbeck, Johnna A., et al.
Publicado: (2019)

Dhb Microcystins Discovered in USA Using an Online Concentration LC–MS/MS Platform
por: Birbeck, Johnna A., et al.
Publicado: (2019)

Chronic Low Dose Oral Exposure to Microcystin-LR Exacerbates Hepatic Injury in a Murine Model of Non-Alcoholic Fatty Liver Disease
por: Lad, Apurva, et al.
Publicado: (2019)

Quantification of microcystin production and biodegradation rates in the western basin of Lake Erie
por: Chaffin, Justin D., et al.
Publicado: (2022)

Antioxidant Therapy Significantly Attenuates Hepatotoxicity following Low Dose Exposure to Microcystin-LR in a Murine Model of Diet-Induced Non-Alcoholic Fatty Liver Disease
por: Lad, Apurva, et al.
Publicado: (2022)

Permanganate Oxidation of Microcystin-LA: Kinetics, Quantification, and Implications for Effective Drinking Water Treatment
por: Szlag, David C., et al.
Publicado: (2019)

Lead exposure induces nitrative stress and disrupts ribbon synapses in the cochlea
por: Rosati, Rita, et al.
Publicado: (2022)

Quantification of Cardiotonic Steroids Potentially Regulated by Paraoxonase 3 in a Rat Model of Chronic Kidney Disease Using UHPLC-Orbitrap-MS
por: Lamichhane, Sabitri, et al.
Publicado: (2022)

As We Drink and Breathe: Adverse Health Effects of Microcystins and Other Harmful Algal Bloom Toxins in the Liver, Gut, Lungs and Beyond
por: Lad, Apurva, et al.
Publicado: (2022)

Comparison of Protein Phosphatase Inhibition Assay with LC-MS/MS for Diagnosis of Microcystin Toxicosis in Veterinary Cases
por: Moore, Caroline E., et al.
Publicado: (2016)

Comparative Studies on the pH Dependence of D(OW) of Microcystin-RR and -LR Using LC-MS
por: Liang, Gaodao, et al.
Publicado: (2011)

Stoichiometric Quantification of Akt Phosphorylation Using LC-MS/MS
por: Atrih, Abdelmadjid, et al.
Publicado: (2009)

Pipelines and Systems for Threshold-Avoiding Quantification of LC–MS/MS Data
por: Sánchez Brotons, Alejandro, et al.
Publicado: (2021)

Estimation of measurement uncertainty for the quantification of protein by ID-LC–MS/MS
por: Beasley-Green, Ashley, et al.
Publicado: (2023)

Novel Microcystins from Planktothrix prolifica NIVA-CYA 544 Identified by LC-MS/MS, Functional Group Derivatization and (15)N-labeling
por: Mallia, Vittoria, et al.
Publicado: (2019)

Quantification of cGMP in human plasma by isotope dilution LC-MS/MS
por: Martens-Lobenhoffer, Jens, et al.
Publicado: (2009)

LC-MS/MS Quantification of Tramadol and Gabapentin Utilizing Solid Phase Extraction
por: Nagaraju, Pappula, et al.
Publicado: (2018)

Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma
por: Temova Rakuša, Žane, et al.
Publicado: (2019)

Modern Approaches in the Identification and Quantification of Immunogenic Peptides in Cereals by LC-MS/MS
por: Alves, Thais O., et al.
Publicado: (2019)

LC-MS/MS for Ultra-Sensitive Quantification of Multiple Estrogens in the Blood and Brain
por: Jalabert, Cecilia, et al.
Publicado: (2021)

Rapid LC-MS/MS Bosutinib Quantification with Applications in Metabolic Stability Estimation
por: Attwa, Mohamed W., et al.
Publicado: (2023)

Development, Validation, and Comparison of Two Mass Spectrometry Methods (LC-MS/HRMS and LC-MS/MS) for the Quantification of Rituximab in Human Plasma
por: Millet, Aurélien, et al.
Publicado: (2021)

Simultaneous Analysis of Cyanotoxins β-N-methylamino-L-alanine (BMAA) and Microcystins-RR, -LR, and -YR Using Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS)
por: Pravadali-Cekic, Sercan, et al.
Publicado: (2023)

CD40 Receptor Knockout Protects against Microcystin-LR (MC-LR) Prolongation and Exacerbation of Dextran Sulfate Sodium (DSS)-Induced Colitis
por: Su, Robin C., et al.
Publicado: (2020)

An in-depth analysis of four classes of antidepressants quantification from human serum using LC–MS/MS
por: Fariha, Ramisa, et al.
Publicado: (2023)

Development and validation of a LC–MS/MS method for quantification of hetrombopag for pharmacokinetics study
por: Chen, Tao, et al.
Publicado: (2015)

Validated LC-MS/MS Method for the Quantification of Ponatinib in Plasma: Application to Metabolic Stability
por: Kadi, Adnan A., et al.
Publicado: (2016)

Quantification of tolvaptan in rabbit plasma by LC–MS/MS: Application to a pharmacokinetic study()
por: Moola, Kumar S., et al.
Publicado: (2015)

Identification and Quantification of Enniatins and Beauvericin in Animal Feeds and Their Ingredients by LC-QTRAP/MS/MS
por: Tolosa, Josefa, et al.
Publicado: (2019)

New method for quantification of gasotransmitter hydrogen sulfide in biological matrices by LC-MS/MS
por: Tan, Bo, et al.
Publicado: (2017)

A Simple LC-MS/MS Method for the Quantification of PDA-66 in Human Plasma
por: Schwarz, Rico, et al.
Publicado: (2022)

Investigation of the metabolic stability of olmutinib by validated LC-MS/MS: quantification in human plasma
por: Attwa, Mohamed W., et al.
Publicado: (2018)

Multiplexed quantification of insulin and C-peptide by LC-MS/MS without the use of antibodies
por: Foulon, North, et al.
Publicado: (2022)

Ultrasensitive Quantification of Multiple Estrogens in Songbird Blood and Microdissected Brain by LC-MS/MS
por: Jalabert, Cecilia, et al.
Publicado: (2022)

Development and validation of an LC–MS/MS method for the quantification of artificial sweeteners in human matrices
por: Greibe, Eva, et al.
Publicado: (2022)

A multi-analyte LC-MS/MS method for screening and quantification of nitrosamines in sartans
por: Chang, Shu-Han, et al.
Publicado: (2020)

Simultaneous quantification of nirmatrelvir and ritonavir by LC-MS/MS in patients treated for COVID-19
por: Martens-Lobenhoffer, Jens, et al.
Publicado: (2022)

Quantification and reporting of vitamin D concentrations measured in human milk by LC–MS/MS
por: Jones, Kerry S., et al.
Publicado: (2023)

Deep Cyanobacteria Layers: An Overlooked Aspect of Managing Risks of Cyanobacteria
por: Erratt, Kevin J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0jqitp9kp2otaugh46opcos1s5