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Survival of Human Norovirus Surrogates in Water upon Exposure to Thermal and Non-Thermal Antiviral Treatments
Human noroviruses are the leading cause of foodborne gastroenteritis worldwide and disease outbreaks have been linked to contaminated surface waters as well as to produce consumption. Noroviruses are extremely stable in water and their presence is being detected with increasing frequency, yet there...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232373/ https://www.ncbi.nlm.nih.gov/pubmed/32325896 http://dx.doi.org/10.3390/v12040461 |
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author | Zhu, Shu Barnes, Candace Bhar, Sutonuka Hoyeck, Papa Galbraith, Annalise N. Devabhaktuni, Divya Karst, Stephanie M. Montazeri, Naim Jones, Melissa K. |
author_facet | Zhu, Shu Barnes, Candace Bhar, Sutonuka Hoyeck, Papa Galbraith, Annalise N. Devabhaktuni, Divya Karst, Stephanie M. Montazeri, Naim Jones, Melissa K. |
author_sort | Zhu, Shu |
collection | PubMed |
description | Human noroviruses are the leading cause of foodborne gastroenteritis worldwide and disease outbreaks have been linked to contaminated surface waters as well as to produce consumption. Noroviruses are extremely stable in water and their presence is being detected with increasing frequency, yet there are no viable methods for reducing norovirus contamination in environmental water. Despite this, there is little knowledge regarding the physical and chemical factors that influence the environmental persistence of this pathogen. This study evaluated the impact of common chemical and physical properties of surface water on the stability of murine norovirus and examined the effect of food-safe chitosan microparticles on infectivity of two human norovirus surrogates. While chemical additives had a minor impact on virus survival, chitosan microparticles significantly reduced infectious titers of both murine norovirus and MS2 bacteriophage. |
format | Online Article Text |
id | pubmed-7232373 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72323732020-05-22 Survival of Human Norovirus Surrogates in Water upon Exposure to Thermal and Non-Thermal Antiviral Treatments Zhu, Shu Barnes, Candace Bhar, Sutonuka Hoyeck, Papa Galbraith, Annalise N. Devabhaktuni, Divya Karst, Stephanie M. Montazeri, Naim Jones, Melissa K. Viruses Article Human noroviruses are the leading cause of foodborne gastroenteritis worldwide and disease outbreaks have been linked to contaminated surface waters as well as to produce consumption. Noroviruses are extremely stable in water and their presence is being detected with increasing frequency, yet there are no viable methods for reducing norovirus contamination in environmental water. Despite this, there is little knowledge regarding the physical and chemical factors that influence the environmental persistence of this pathogen. This study evaluated the impact of common chemical and physical properties of surface water on the stability of murine norovirus and examined the effect of food-safe chitosan microparticles on infectivity of two human norovirus surrogates. While chemical additives had a minor impact on virus survival, chitosan microparticles significantly reduced infectious titers of both murine norovirus and MS2 bacteriophage. MDPI 2020-04-19 /pmc/articles/PMC7232373/ /pubmed/32325896 http://dx.doi.org/10.3390/v12040461 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhu, Shu Barnes, Candace Bhar, Sutonuka Hoyeck, Papa Galbraith, Annalise N. Devabhaktuni, Divya Karst, Stephanie M. Montazeri, Naim Jones, Melissa K. Survival of Human Norovirus Surrogates in Water upon Exposure to Thermal and Non-Thermal Antiviral Treatments |
title | Survival of Human Norovirus Surrogates in Water upon Exposure to Thermal and Non-Thermal Antiviral Treatments |
title_full | Survival of Human Norovirus Surrogates in Water upon Exposure to Thermal and Non-Thermal Antiviral Treatments |
title_fullStr | Survival of Human Norovirus Surrogates in Water upon Exposure to Thermal and Non-Thermal Antiviral Treatments |
title_full_unstemmed | Survival of Human Norovirus Surrogates in Water upon Exposure to Thermal and Non-Thermal Antiviral Treatments |
title_short | Survival of Human Norovirus Surrogates in Water upon Exposure to Thermal and Non-Thermal Antiviral Treatments |
title_sort | survival of human norovirus surrogates in water upon exposure to thermal and non-thermal antiviral treatments |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232373/ https://www.ncbi.nlm.nih.gov/pubmed/32325896 http://dx.doi.org/10.3390/v12040461 |
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