Cysteine Residues in Helicobacter pylori Adhesin HopQ Are Required for CEACAM–HopQ Interaction and Subsequent CagA Translocation

Attachment to the host gastric mucosa is a key step in Helicobacter pylori infection. Recently, a novel adhesin, HopQ, was shown to bind distinct host CEACAM proteins—an interaction that was found to be essential for the translocation of CagA, a key virulence factor of H. pylori. The HopQ–CEACAM1 co...

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Detalles Bibliográficos
Autores principales: Hamway, Youssef, Taxauer, Karin, Moonens, Kristof, Neumeyer, Victoria, Fischer, Wolfgang, Schmitt, Verena, Singer, Bernhard B., Remaut, Han, Gerhard, Markus, Mejías-Luque, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232459/
https://www.ncbi.nlm.nih.gov/pubmed/32218315
http://dx.doi.org/10.3390/microorganisms8040465

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