Novel Toscana Virus Reverse Genetics System Establishes NSs as an Antagonist of Type I Interferon Responses

The sand fly-borne Toscana virus (TOSV) is the major cause of human meningoencephalitis in the Mediterranean basin during the summer season. In this work, we have developed a T7 RNA polymerase-driven reverse genetics system to recover infectious particles of a lineage B strain of TOSV. The viral pro...

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Detalles Bibliográficos
Autores principales: Woelfl, Franziska, Léger, Psylvia, Oreshkova, Nadia, Pahmeier, Felix, Windhaber, Stefan, Koch, Jana, Stanifer, Megan, Roman Sosa, Gleyder, Uckeley, Zina M., Rey, Felix A., Boulant, Steeve, Kortekaas, Jeroen, Wichgers Schreur, Paul J., Lozach, Pierre-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232479/
https://www.ncbi.nlm.nih.gov/pubmed/32260371
http://dx.doi.org/10.3390/v12040400

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