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A Mini Review on Microcystins and Bacterial Degradation

Microcystins (MCs) classified as hepatotoxic and carcinogenic are the most commonly reported cyanobacterial toxins found in the environment. Microcystis sp. possessing a series of MC synthesis genes (mcyA-mcyJ) are well documented for their excessive abundance, numerous bloom occurrences and MC prod...

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Detalles Bibliográficos
Autores principales: Massey, Isaac Yaw, Yang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232508/
https://www.ncbi.nlm.nih.gov/pubmed/32326338
http://dx.doi.org/10.3390/toxins12040268
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author Massey, Isaac Yaw
Yang, Fei
author_facet Massey, Isaac Yaw
Yang, Fei
author_sort Massey, Isaac Yaw
collection PubMed
description Microcystins (MCs) classified as hepatotoxic and carcinogenic are the most commonly reported cyanobacterial toxins found in the environment. Microcystis sp. possessing a series of MC synthesis genes (mcyA-mcyJ) are well documented for their excessive abundance, numerous bloom occurrences and MC producing capacity. About 246 variants of MC which exert severe animal and human health hazards through the inhibition of protein phosphatases (PP1 and PP2A) have been characterized. To minimize and prevent MC health consequences, the World Health Organization proposed 1 µg/L MC guidelines for safe drinking water quality. Further the utilization of bacteria that represent a promising biological treatment approach to degrade and remove MC from water bodies without harming the environment has gained global attention. Thus the present review described toxic effects and bacterial degradation of MCs.
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spelling pubmed-72325082020-05-22 A Mini Review on Microcystins and Bacterial Degradation Massey, Isaac Yaw Yang, Fei Toxins (Basel) Review Microcystins (MCs) classified as hepatotoxic and carcinogenic are the most commonly reported cyanobacterial toxins found in the environment. Microcystis sp. possessing a series of MC synthesis genes (mcyA-mcyJ) are well documented for their excessive abundance, numerous bloom occurrences and MC producing capacity. About 246 variants of MC which exert severe animal and human health hazards through the inhibition of protein phosphatases (PP1 and PP2A) have been characterized. To minimize and prevent MC health consequences, the World Health Organization proposed 1 µg/L MC guidelines for safe drinking water quality. Further the utilization of bacteria that represent a promising biological treatment approach to degrade and remove MC from water bodies without harming the environment has gained global attention. Thus the present review described toxic effects and bacterial degradation of MCs. MDPI 2020-04-21 /pmc/articles/PMC7232508/ /pubmed/32326338 http://dx.doi.org/10.3390/toxins12040268 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Massey, Isaac Yaw
Yang, Fei
A Mini Review on Microcystins and Bacterial Degradation
title A Mini Review on Microcystins and Bacterial Degradation
title_full A Mini Review on Microcystins and Bacterial Degradation
title_fullStr A Mini Review on Microcystins and Bacterial Degradation
title_full_unstemmed A Mini Review on Microcystins and Bacterial Degradation
title_short A Mini Review on Microcystins and Bacterial Degradation
title_sort mini review on microcystins and bacterial degradation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232508/
https://www.ncbi.nlm.nih.gov/pubmed/32326338
http://dx.doi.org/10.3390/toxins12040268
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