IL-22 Paucity in APECED Is Associated With Mucosal and Microbial Alterations in Oral Cavity

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is caused by recessive mutations in the AIRE gene. The hallmark of the disease is the production of highly neutralizing autoantibodies against type I interferons and IL-22. Considering the importance of IL-22 in maintaining muco...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaleviste, Epp, Rühlemann, Malte, Kärner, Jaanika, Haljasmägi, Liis, Tserel, Liina, Org, Elin, Trebušak Podkrajšek, Katarina, Battelino, Tadej, Bang, Corinna, Franke, Andre, Peterson, Pärt, Kisand, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232598/
https://www.ncbi.nlm.nih.gov/pubmed/32477345
http://dx.doi.org/10.3389/fimmu.2020.00838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232598/
https://www.ncbi.nlm.nih.gov/pubmed/32477345
http://dx.doi.org/10.3389/fimmu.2020.00838

Ejemplares similares