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High-Throughput In Vitro, Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction

Adeno-associated virus (AAV) vectors are quickly becoming the vectors of choice for therapeutic gene delivery. To date, hundreds of natural isolates and bioengineered variants have been reported. While factors such as high production titer and low immunoreactivity are important to consider, the abil...

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Detalles Bibliográficos
Autores principales: Westhaus, Adrian, Cabanes-Creus, Marti, Rybicki, Arkadiusz, Baltazar, Grober, Navarro, Renina Gale, Zhu, Erhua, Drouyer, Matthieu, Knight, Maddison, Albu, Razvan F., Ng, Boaz H., Kalajdzic, Predrag, Kwiatek, Magdalena, Hsu, Kenneth, Santilli, Giorgia, Gold, Wendy, Kramer, Belinda, Gonzalez-Cordero, Anai, Thrasher, Adrian J., Alexander, Ian E., Lisowski, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232709/
https://www.ncbi.nlm.nih.gov/pubmed/32000541
http://dx.doi.org/10.1089/hum.2019.264