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Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review

Thyroid cancer is the most common endocrine malignancy, presenting with 23 500 new cases per year in the United States. About 7-23% of the patients will present recurrent metastases disease during follow-up. The classic variant of papillary carcinoma is less aggressive compared to its other variants...

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Autores principales: Maffuz-Aziz, Antonio, Garnica, Gabriel, López-Hernández, Silvia, Pineda-Diaz, Janet, Baquera-Heredia, Javier, López-Jiménez, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232720/
https://www.ncbi.nlm.nih.gov/pubmed/32455035
http://dx.doi.org/10.1155/2020/2084847
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author Maffuz-Aziz, Antonio
Garnica, Gabriel
López-Hernández, Silvia
Pineda-Diaz, Janet
Baquera-Heredia, Javier
López-Jiménez, Patricia
author_facet Maffuz-Aziz, Antonio
Garnica, Gabriel
López-Hernández, Silvia
Pineda-Diaz, Janet
Baquera-Heredia, Javier
López-Jiménez, Patricia
author_sort Maffuz-Aziz, Antonio
collection PubMed
description Thyroid cancer is the most common endocrine malignancy, presenting with 23 500 new cases per year in the United States. About 7-23% of the patients will present recurrent metastases disease during follow-up. The classic variant of papillary carcinoma is less aggressive compared to its other variants like diffuse sclerosing, tall cell or columnar cell, and insular variants, and the sites to which this metastasizes is already well identified. Metastasis to the spleen is an extremely rare manifestation of papillary thyroid cancer. To date, only 3 cases have been reported in the literature. Herein, we present a 52-year-old male, who developed spleen metastases, 2.4 years after total thyroidectomy and central neck dissection followed by radioactive iodine ablation and seven months after treatment with sorafenib for lung metastases. The splenic lesion was detected in surveillance studies. This case highlights that splenic metastasis, although rare, may occur even in a patient with a locoregional and systemic controlled thyroid cancer and that it can be treated safely with surgical resection.
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spelling pubmed-72327202020-05-22 Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review Maffuz-Aziz, Antonio Garnica, Gabriel López-Hernández, Silvia Pineda-Diaz, Janet Baquera-Heredia, Javier López-Jiménez, Patricia Case Rep Oncol Med Case Report Thyroid cancer is the most common endocrine malignancy, presenting with 23 500 new cases per year in the United States. About 7-23% of the patients will present recurrent metastases disease during follow-up. The classic variant of papillary carcinoma is less aggressive compared to its other variants like diffuse sclerosing, tall cell or columnar cell, and insular variants, and the sites to which this metastasizes is already well identified. Metastasis to the spleen is an extremely rare manifestation of papillary thyroid cancer. To date, only 3 cases have been reported in the literature. Herein, we present a 52-year-old male, who developed spleen metastases, 2.4 years after total thyroidectomy and central neck dissection followed by radioactive iodine ablation and seven months after treatment with sorafenib for lung metastases. The splenic lesion was detected in surveillance studies. This case highlights that splenic metastasis, although rare, may occur even in a patient with a locoregional and systemic controlled thyroid cancer and that it can be treated safely with surgical resection. Hindawi 2020-05-04 /pmc/articles/PMC7232720/ /pubmed/32455035 http://dx.doi.org/10.1155/2020/2084847 Text en Copyright © 2020 Antonio Maffuz-Aziz et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Maffuz-Aziz, Antonio
Garnica, Gabriel
López-Hernández, Silvia
Pineda-Diaz, Janet
Baquera-Heredia, Javier
López-Jiménez, Patricia
Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review
title Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review
title_full Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review
title_fullStr Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review
title_full_unstemmed Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review
title_short Splenectomy for Solitary Splenic Metastasis in Recurrent Papillary Thyroid Cancer. A Case Report and Literature Review
title_sort splenectomy for solitary splenic metastasis in recurrent papillary thyroid cancer. a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232720/
https://www.ncbi.nlm.nih.gov/pubmed/32455035
http://dx.doi.org/10.1155/2020/2084847
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