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Validation and noninvasive kinetic modeling of [(11)C]UCB-J PET imaging in mice
Synaptic pathology is associated with several brain disorders, thus positron emission tomography (PET) imaging of synaptic vesicle glycoprotein 2A (SV2A) using the radioligand [(11)C]UCB-J may provide a tool to measure synaptic alterations. Given the pivotal role of mouse models in understanding neu...
Autores principales: | Bertoglio, Daniele, Verhaeghe, Jeroen, Miranda, Alan, Kertesz, Istvan, Cybulska, Klaudia, Korat, Špela, Wyffels, Leonie, Stroobants, Sigrid, Mrzljak, Ladislav, Dominguez, Celia, Liu, Longbin, Skinbjerg, Mette, Munoz-Sanjuan, Ignacio, Staelens, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232782/ https://www.ncbi.nlm.nih.gov/pubmed/31307287 http://dx.doi.org/10.1177/0271678X19864081 |
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