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Synthesis and biological evaluation of a new series of 1-aryl-3-[4-(pyridin-2-ylmethoxy)phenyl]urea derivatives as new anticancer agents

The diaryl ureas are very important fragments in medicinal chemistry. By means of computer-aided design, 1-aryl-3-[4-(pyridin-2-ylmethoxy)phenyl]urea derivatives were designed and synthesized, and evaluated for their antiproliferative activity against A549, HCT-116, PC-3 cancer cell lines, and HL770...

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Detalles Bibliográficos
Autores principales:	Feng, Jian, Li, Tai, Liang, Shishao, Zhang, Chuanming, Tan, Xiaoyu, Ding, Ning, Wang, Xin, Liu, Xiaoping, Hu, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232929/ https://www.ncbi.nlm.nih.gov/pubmed/32427204 http://dx.doi.org/10.1007/s00044-020-02554-z

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