Cargando…

Effects of an injectable long-acting formulation of ivermectin on Onchocerca ochengi in zebu cattle

The availability of a safe macrofilaricidal drug would help to accelerate onchocerciasis elimination. A trial was conducted in Cameroon to evaluate the effects of a subcutaneous injectable long-acting formulation of ivermectin (LAFI) on the microfilariae (mf) and adult stages of Onchocerca ochengi....

Descripción completa

Detalles Bibliográficos
Autores principales:	Boussinesq, Michel, Enyong, Peter, Chounna-Ndongmo, Patrick, Njouendou, Abdel-Jelil, Pion, Sébastien David, Rech, Anthony, Roberge, Christophe, Gaudriault, Georges, Wanji, Samuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	EDP Sciences 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233116/ https://www.ncbi.nlm.nih.gov/pubmed/32420864 http://dx.doi.org/10.1051/parasite/2020036

Ejemplares similares

Further evidence of the cross-reactivity of the Binax NOW® Filariasis ICT cards to non-Wuchereria bancrofti filariae: experimental studies with Loa loa and Onchocerca ochengi
por: Wanji, Samuel, et al.
Publicado: (2016)

Galectins from Onchocerca ochengi and O. volvulus and their immune recognition by Wistar rats, Gudali zebu cattle and human hosts
por: Ngwasiri, Ngwafu Nancy, et al.
Publicado: (2021)

Correction to: Galectins from Onchocerca ochengi and O. volvulus and their immune recognition by Wistar rats, Gudali zebu cattle and human hosts
por: Ngwasiri, Ngwafu Nancy, et al.
Publicado: (2021)

Stage-specific Proteomes from Onchocerca ochengi, Sister Species of the Human River Blindness Parasite, Uncover Adaptations to a Nodular Lifestyle
por: Armstrong, Stuart D., et al.
Publicado: (2016)

Dynamics of Onchocerca volvulus Microfilarial Densities after Ivermectin Treatment in an Ivermectin-naïve and a Multiply Treated Population from Cameroon
por: Pion, Sébastien D. S., et al.
Publicado: (2013)

Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment
por: Abong, Raphael Awah, et al.
Publicado: (2020)

Correction to: Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment
por: Abong, Raphael Awah, et al.
Publicado: (2021)

Impact of repeated annual community directed treatment with ivermectin on loiasis parasitological indicators in Cameroon: Implications for onchocerciasis and lymphatic filariasis elimination in areas co-endemic with Loa loa in Africa
por: Wanji, Samuel, et al.
Publicado: (2018)

Reproductive Status of Onchocerca volvulus after Ivermectin Treatment in an Ivermectin-Naïve and a Frequently Treated Population from Cameroon
por: Nana-Djeunga, Hugues C., et al.
Publicado: (2014)

Genetic Selection of Low Fertile Onchocerca volvulus by Ivermectin Treatment
por: Bourguinat, Catherine, et al.
Publicado: (2007)

Depressive Symptoms Amongst People with Podoconiosis and Lower Limb Lymphoedema of Other Cause in Cameroon: A Cross-Sectional Study
por: Semrau, Maya, et al.
Publicado: (2019)

Full mitochondrial and nuclear genome comparison confirms that Onchocerca sp. “Siisa” is Onchocerca ochengi
por: Jaleta, Tegegn G., et al.
Publicado: (2018)

Onchocerca ochengi male worms implanted in SCID mice and Gerbil: Relationship between microfilaridermia status of cows, nodular worm viability and fertility and worm survival in the rodents
por: Akumtoh, Desmond N., et al.
Publicado: (2021)

Onchocerca - infected cattle produce strong antibody responses to excretory-secretory proteins released from adult male Onchocerca ochengi worms
por: Boursou, Djafsia, et al.
Publicado: (2018)

UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle
por: deC Bronsvoort, Barend M, et al.
Publicado: (2008)

Selective activity of extracts of Margaritaria discoidea and Homalium africanum on Onchocerca ochengi
por: Cho-Ngwa, Fidelis, et al.
Publicado: (2010)

Effect of flubendazole on developing stages of Loa loa in vitro and in vivo: a new approach for screening filaricidal agents
por: Fombad, Fanny Fri, et al.
Publicado: (2019)

Development and validation of an Onchocerca ochengi microfilarial hamster model for onchocerciasis drug screens
por: Mbah, Glory Enjong, et al.
Publicado: (2016)

Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle
por: deC Bronsvoort, Barend M, et al.
Publicado: (2005)

Urine metabolites for the identification of Onchocerca volvulus infections in patients from Cameroon
por: Wewer, Vera, et al.
Publicado: (2021)

Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening
por: Gandjui, Narcisse V. T., et al.
Publicado: (2021)

Antifilarial Activity of the Methanolic Extract of Indigofera tinctoria (Fabaceae) on Bovine Parasites (Onchocerca ochengi)
por: Rakwa, Enock Enock, et al.
Publicado: (2022)

Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With Onchocerca ochengi
por: Zhan, Bin, et al.
Publicado: (2022)

Update on the biology and ecology of Culicoides species in the South-West region of Cameroon with implications on the transmission of Mansonella perstans
por: Wanji, Samuel, et al.
Publicado: (2019)

Lipid profiling of the filarial nematodes Onchocerca volvulus, Onchocerca ochengi and Litomosoides sigmodontis reveals the accumulation of nematode-specific ether phospholipids in the host
por: Wewer, Vera, et al.
Publicado: (2017)

Proof-of-concept study for a long-acting formulation of ivermectin injected in cattle as a complementary malaria vector control tool
por: Pooda, Sié Hermann, et al.
Publicado: (2023)

Dataset on in vitro maintenance of Mansonella perstans microfilariae and drug testing
por: Njouendou, Abdel Jelil, et al.
Publicado: (2019)

In vitro anti-Onchocerca ochengi activities of extracts and chromatographic fractions of Craterispermum laurinum and Morinda lucida
por: Samje, Moses, et al.
Publicado: (2014)

Development and validation of an Onchocerca ochengi adult male worm gerbil model for macrofilaricidal drug screening
por: Cho-Ngwa, Fidelis, et al.
Publicado: (2019)

Evaluation of in vitro culture systems for the maintenance of microfilariae and infective larvae of Loa loa
por: Zofou, Denis, et al.
Publicado: (2018)

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity
por: Doyle, Stephen R., et al.
Publicado: (2017)

Energy metabolism of pregnant zebu and crossbred zebu dairy cattle
por: Lage, Helena Ferreira, et al.
Publicado: (2021)

Cross-Reactivity of Filariais ICT Cards in Areas of Contrasting Endemicity of Loa loa and Mansonella perstans in Cameroon: Implications for Shrinking of the Lymphatic Filariasis Map in the Central African Region
por: Wanji, Samuel, et al.
Publicado: (2015)

Successful long-term maintenance of Mansonella perstans in an in vitro culture system
por: Njouendou, Abdel Jelil, et al.
Publicado: (2017)

Mansonella perstans microfilaremic individuals are characterized by enhanced type 2 helper T and regulatory T and B cell subsets and dampened systemic innate and adaptive immune responses
por: Ritter, Manuel, et al.
Publicado: (2018)

Filaricidal activities on Onchocerca ochengi and Loa loa, toxicity and phytochemical screening of extracts of Tragia benthami and Piper umbellatum
por: Cho-Ngwa, Fidelis, et al.
Publicado: (2016)

Characterization of a novel glycosylated glutathione transferase of Onchocerca ochengi, closest relative of the human river blindness parasite
por: Rose, Clair, et al.
Publicado: (2019)

Programmatic factors associated with the limited impact of Community-Directed Treatment with Ivermectin to control Onchocerciasis in three drainage basins of South West Cameroon
por: Duamor, Christian Tetteh, et al.
Publicado: (2017)

A worm's best friend: recruitment of neutrophils by Wolbachia confounds eosinophil degranulation against the filarial nematode Onchocerca ochengi
por: Hansen, Rowena D. E., et al.
Publicado: (2011)

Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis
por: Bah, Germanus S., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pvs27t5biuf1jac4ebvmh3edei