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Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex

The androgen receptor (AR) is a major driver of prostate cancer development and progression. Men who develop advanced prostate cancer often have long-term cancer control when treated with androgen-deprivation therapies (ADT). Still, their disease inevitably becomes resistant to ADT and progresses to...

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Detalles Bibliográficos
Autores principales: Miranti, Cindy K., Moore, Sara, Kim, Yongeun, Chappeta, Venkateshwar Reddy, Wu, Kui, De, Biswanath, Gokhale, Vijay, Hurley, Laurence H., Reyes-Reyes, Elsa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233804/
https://www.ncbi.nlm.nih.gov/pubmed/32477465
http://dx.doi.org/10.18632/oncotarget.27589