Cargando…

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma

Ewing sarcoma (ES) is a malignant pediatric bone and soft tissue tumor. Patients with metastatic ES have a dismal outcome which has not been improved in decades. The major challenge in the treatment of metastatic ES is the lack of specific targets and rational combinatorial therapy. We recently foun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Wen, Xu, Changxin, Phillips, Sarah, Gardenswartz, Aliza, Rosenblum, Jeremy M., Ayello, Janet, Lessnick, Stephen L., Hao, Huai-Xiang, Cairo, Mitchell S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233808/ https://www.ncbi.nlm.nih.gov/pubmed/32477459 http://dx.doi.org/10.18632/oncotarget.27571

Ejemplares similares

Targeting Glutathione S-transferase M4 in Ewing sarcoma
por: Zhuo, Rupeng, et al.
Publicado: (2014)

A humanized orthotopic mouse model for preclinical evaluation of immunotherapy in Ewing sarcoma
por: Luo, Wen, et al.
Publicado: (2023)

Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis
por: Kowalewski, Ashley A., et al.
Publicado: (2011)

Recent advances in targeted therapy for Ewing sarcoma
por: Pishas, Kathleen I., et al.
Publicado: (2016)

Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation
por: Pishas, Kathleen I., et al.
Publicado: (2018)

Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting
por: Theisen, Emily R., et al.
Publicado: (2016)

Antibody detection of translocations in Ewing sarcoma
por: Luo, Wen, et al.
Publicado: (2012)

Microsatellites with Macro-Influence in Ewing Sarcoma
por: Monument, Michael J., et al.
Publicado: (2012)

Is There a Predisposition Gene for Ewing's Sarcoma?
por: Randall, R. L., et al.
Publicado: (2010)

SERUM VALUES OF ALKALINE PHOSPHATASE AND LACTATE DEHYDROGENASE IN EWING'S SARCOMA
por: Baptista, André Mathias, et al.
Publicado: (2016)

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma
por: Patel, Priyal O., et al.
Publicado: (2019)

The Landscape of Regulatory Noncoding RNAs in Ewing’s Sarcoma
por: Barrett, Connor, et al.
Publicado: (2021)

Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma
por: Sankar, Savita, et al.
Publicado: (2012)

Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma
por: Weaver, Davis T., et al.
Publicado: (2021)

C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells
por: Gardiner, Jamie D., et al.
Publicado: (2017)

BCL11B Is Up-Regulated by EWS/FLI and Contributes to the Transformed Phenotype in Ewing Sarcoma
por: Wiles, Elizabeth T., et al.
Publicado: (2013)

EWS-FLI1 regulates and cooperates with core regulatory circuitry in Ewing sarcoma
por: Shi, Xianping, et al.
Publicado: (2020)

Identification and characterization of slow-cycling cells in Ewing sarcoma
por: Yahiro, Shunsuke, et al.
Publicado: (2022)

Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma
por: Johnson, Kirsten M., et al.
Publicado: (2017)

Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1)
por: Sukackaite, Rasa, et al.
Publicado: (2017)

Increased risk for other cancers in individuals with Ewing sarcoma and their relatives
por: Abbott, Diana, et al.
Publicado: (2019)

EWS/FLI Mediates Transcriptional Repression via NKX2.2 during Oncogenic Transformation in Ewing's Sarcoma
por: Owen, Leah A., et al.
Publicado: (2008)

EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma
por: Fadul, John, et al.
Publicado: (2015)

A Decade in Banking Ewing Sarcoma: A Report from the Children’s Oncology Group
por: Borinstein, Scott C., et al.
Publicado: (2013)

Identifying States of Collateral Sensitivity during the Evolution of Therapeutic Resistance in Ewing's Sarcoma
por: Scarborough, Jessica A., et al.
Publicado: (2020)

Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases
por: Tavakkoli, Montreh, et al.
Publicado: (2018)

Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children’s Oncology Group (COG) New Agents for Ewing Sarcoma Task Force
por: Bailey, Kelly, et al.
Publicado: (2019)

FOXM1 Is an Oncogenic Mediator in Ewing Sarcoma
por: Christensen, Laura, et al.
Publicado: (2013)

WT1 regulates angiogenesis in Ewing Sarcoma
por: Katuri, Varalakshmi, et al.
Publicado: (2014)

Survey of Paediatric Oncologists and Pathologists regarding Their Views and Experiences with Variant Translocations in Ewing and Ewing-Like Sarcoma: A Report of the Children's Oncology Group
por: Kinnaman, Michael D., et al.
Publicado: (2020)

The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma
por: Boone, Megann A., et al.
Publicado: (2021)

Protein Phosphatase 1 Regulatory Subunit 3: A Prognostic Biomarker in Stomach Adenocarcinoma
por: Zhu, Ya-Zhen, et al.
Publicado: (2022)

Ewing's sarcoma of zygoma
por: Deshingkar, SA, et al.
Publicado: (2009)

Ewing's sarcoma of the mandible
por: Rao, B. H. Sripathi, et al.
Publicado: (2011)

Chemotherapy in Ewing’s sarcoma
por: Jain, Sandeep, et al.
Publicado: (2010)

The Biology of Ewing Sarcoma
por: Ross, Keir A., et al.
Publicado: (2013)

Ewing's Sarcoma of the Finger
por: Gökalp, Mehmet Ata, et al.
Publicado: (2014)

Ewing's Sarcoma of the Calcaneum
por: Sherif, P Ajmal, et al.
Publicado: (2017)

Paratesticular Ewing's sarcoma
por: Koshevarova, Victoria, et al.
Publicado: (2023)

Biomarkers in Ewing Sarcoma: The Promise and Challenge of Personalized Medicine. A Report from the Children’s Oncology Group
por: Shukla, Neerav, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_b7q640n3rlcqdc4edmg1id48vi