O11.3. SYNAPTIC MARKER PROTEIN SV2A IS REDUCED IN SCHIZOPHRENIA IN VIVO AND UNAFFECTED BY ANTIPSYCHOTICS IN RATS

BACKGROUND: The synaptic dysfunction hypothesis of schizophrenia is supported by multiple lines of evidence. However, in vivo evidence is lacking. Moreover, it is not known if antipsychotics alter synaptic protein levels. We addressed this in a combined clinical study using [11C]UCB-J, a positron em...

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Detalles Bibliográficos
Autores principales: Chika Onwordi, Ellis, Halff, Els, Whitehurst, Thomas, Mansur, Ayla, Cotel, Marie-Caroline, Wells, Lisa, Creeney, Hannah, Bonsall, David, Rogdaki, Maria, Shatalina, Ekaterina, Reis Marques, Tiago, Rabiner, Eugenii, Gunn, Roger, Natesan, Sridhar, Vernon, Anthony, Howes, Oliver D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Oral Session: Digital Health/Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233999/
http://dx.doi.org/10.1093/schbul/sbaa028.063

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