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O7.2. MENTAL HEALTH AND SOMATIC STATUS OF YOUNG CHILDREN (0–6 YEARS) BORN TO PARENTS WITH SEVERE MENTAL ILLNESSES - A NATIONWIDE DANISH REGISTER STUDY

BACKGROUND: Children born to parents with severe mental illness like schizophrenia, bipolar disorder or recurrent major depression have been shown to have a higher risk, not only for developing a mental illness themselves in adulthood (Rasic) but also in childhood and adolescence. Less is known abou...

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Autores principales: Amalie Thorup, Anne, Davidsen, Kirstine, Ranning, Anne, Jennes-Foli, Pia, Harder, Susanne, Munk Laursen, Thomas, Nordentoft, Merete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234126/
http://dx.doi.org/10.1093/schbul/sbaa028.037
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author Amalie Thorup, Anne
Davidsen, Kirstine
Ranning, Anne
Jennes-Foli, Pia
Harder, Susanne
Munk Laursen, Thomas
Nordentoft, Merete
author_facet Amalie Thorup, Anne
Davidsen, Kirstine
Ranning, Anne
Jennes-Foli, Pia
Harder, Susanne
Munk Laursen, Thomas
Nordentoft, Merete
author_sort Amalie Thorup, Anne
collection PubMed
description BACKGROUND: Children born to parents with severe mental illness like schizophrenia, bipolar disorder or recurrent major depression have been shown to have a higher risk, not only for developing a mental illness themselves in adulthood (Rasic) but also in childhood and adolescence. Less is known about the offspring’s somatic health and very early development processes. Increasing knowledge demonstrate the importance of the very early years of life from birth to age 6 for a healthy and natural brain development and for good life outcomes in general. Thus, more knowledge is needed about this vulnerable period in life, especially for children, who are born with a familial high risk for severe mental illness in order to develop relevant interventions for these children. METHODS: We used Danish registries to evaluate the incidence and the frequencies of early (i.e. age 0–6 years) psychiatric diagnoses of a nationwide cohort of children born to parents with severe mental illness. Further we calculated the frequencies of somatic health problems and compared them to population-based controls. RESULTS: We found increased ORs for children in all three FHR-groups for having received any diagnosis of a mental disorder before age 7 (e.g.: mother depressed, N=1223): OR:2.82 (CI:2.65–2.99), mother bipolar (N=98): OR: 3.06 (CI 2.50–3.76), mother schizophrenia (N=574): OR 5.23 (CI: 4.80–5.69), and similar although a bit smaller ORs if it was the father, who had a diagnosis. Especially ORs for attachment disorder and anxiety were increased but also ORs for eating disorders and sleep disorders were found to be significantly higher than for controls. Odd ratios for somatic disorders were marginally increased for all disorders and also for intoxications and injuries. DISCUSSION: Our results document that children born to parents with severe mental illnesses are vulnerable from the beginning of life, mainly in terms of their mental health but to some extent also in terms of somatic health. Parents who have a severe mental disorder may need extra support in the parenting role to ensure good health for the child.
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spelling pubmed-72341262020-05-23 O7.2. MENTAL HEALTH AND SOMATIC STATUS OF YOUNG CHILDREN (0–6 YEARS) BORN TO PARENTS WITH SEVERE MENTAL ILLNESSES - A NATIONWIDE DANISH REGISTER STUDY Amalie Thorup, Anne Davidsen, Kirstine Ranning, Anne Jennes-Foli, Pia Harder, Susanne Munk Laursen, Thomas Nordentoft, Merete Schizophr Bull Oral Session: Digital Health/Methods BACKGROUND: Children born to parents with severe mental illness like schizophrenia, bipolar disorder or recurrent major depression have been shown to have a higher risk, not only for developing a mental illness themselves in adulthood (Rasic) but also in childhood and adolescence. Less is known about the offspring’s somatic health and very early development processes. Increasing knowledge demonstrate the importance of the very early years of life from birth to age 6 for a healthy and natural brain development and for good life outcomes in general. Thus, more knowledge is needed about this vulnerable period in life, especially for children, who are born with a familial high risk for severe mental illness in order to develop relevant interventions for these children. METHODS: We used Danish registries to evaluate the incidence and the frequencies of early (i.e. age 0–6 years) psychiatric diagnoses of a nationwide cohort of children born to parents with severe mental illness. Further we calculated the frequencies of somatic health problems and compared them to population-based controls. RESULTS: We found increased ORs for children in all three FHR-groups for having received any diagnosis of a mental disorder before age 7 (e.g.: mother depressed, N=1223): OR:2.82 (CI:2.65–2.99), mother bipolar (N=98): OR: 3.06 (CI 2.50–3.76), mother schizophrenia (N=574): OR 5.23 (CI: 4.80–5.69), and similar although a bit smaller ORs if it was the father, who had a diagnosis. Especially ORs for attachment disorder and anxiety were increased but also ORs for eating disorders and sleep disorders were found to be significantly higher than for controls. Odd ratios for somatic disorders were marginally increased for all disorders and also for intoxications and injuries. DISCUSSION: Our results document that children born to parents with severe mental illnesses are vulnerable from the beginning of life, mainly in terms of their mental health but to some extent also in terms of somatic health. Parents who have a severe mental disorder may need extra support in the parenting role to ensure good health for the child. Oxford University Press 2020-05 2020-05-18 /pmc/articles/PMC7234126/ http://dx.doi.org/10.1093/schbul/sbaa028.037 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Oral Session: Digital Health/Methods
Amalie Thorup, Anne
Davidsen, Kirstine
Ranning, Anne
Jennes-Foli, Pia
Harder, Susanne
Munk Laursen, Thomas
Nordentoft, Merete
O7.2. MENTAL HEALTH AND SOMATIC STATUS OF YOUNG CHILDREN (0–6 YEARS) BORN TO PARENTS WITH SEVERE MENTAL ILLNESSES - A NATIONWIDE DANISH REGISTER STUDY
title O7.2. MENTAL HEALTH AND SOMATIC STATUS OF YOUNG CHILDREN (0–6 YEARS) BORN TO PARENTS WITH SEVERE MENTAL ILLNESSES - A NATIONWIDE DANISH REGISTER STUDY
title_full O7.2. MENTAL HEALTH AND SOMATIC STATUS OF YOUNG CHILDREN (0–6 YEARS) BORN TO PARENTS WITH SEVERE MENTAL ILLNESSES - A NATIONWIDE DANISH REGISTER STUDY
title_fullStr O7.2. MENTAL HEALTH AND SOMATIC STATUS OF YOUNG CHILDREN (0–6 YEARS) BORN TO PARENTS WITH SEVERE MENTAL ILLNESSES - A NATIONWIDE DANISH REGISTER STUDY
title_full_unstemmed O7.2. MENTAL HEALTH AND SOMATIC STATUS OF YOUNG CHILDREN (0–6 YEARS) BORN TO PARENTS WITH SEVERE MENTAL ILLNESSES - A NATIONWIDE DANISH REGISTER STUDY
title_short O7.2. MENTAL HEALTH AND SOMATIC STATUS OF YOUNG CHILDREN (0–6 YEARS) BORN TO PARENTS WITH SEVERE MENTAL ILLNESSES - A NATIONWIDE DANISH REGISTER STUDY
title_sort o7.2. mental health and somatic status of young children (0–6 years) born to parents with severe mental illnesses - a nationwide danish register study
topic Oral Session: Digital Health/Methods
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234126/
http://dx.doi.org/10.1093/schbul/sbaa028.037
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