Cargando…
M157. A MULTICENTRE STUDY OF 1H-MRS BRAIN GLUTAMATE LEVELS IN SCHIZOPHRENIA; INVESTIGATING THE EFFECT OF ANTIPSYCHOTIC MEDICATION, SYMPTOM SEVERITY AND AGE
BACKGROUND: Proton Magnetic Resonance Spectroscopy (1H-MRS) studies indicate that altered brain glutamate signalling contributes to the pathophysiology of schizophrenia and treatment response. However it is unclear whether clinical and demographic factors affect glutamate levels in the brain. Here w...
Autores principales: | Merritt, Kate, Aleman, André, Block, Wolfgang, Bloemen, Oswald, Borgan, Faith, Bustillo, Juan, Capizzano, Aristides, Coughlin, Jennifer, de la Fuente-Sandoval, Camilo, Demjaha, Arsime, Do, Kim, Drost, Dick, Falkai, Peter, Galińska, Beata, Gallinat, Jürgen, Gasparovic, Charles, Goto, Naoki, Graff-Guerrero, Ariel, Ho, Beng-Choon, Howes, Oliver, Jauhar, Sameer, Kato, Tadafumi, Kaufmann, Charles, Egerton, Alice |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234284/ http://dx.doi.org/10.1093/schbul/sbaa030.469 |
Ejemplares similares
-
Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data
por: Merritt, Kate, et al.
Publicado: (2021) -
Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis
por: Merritt, Kate, et al.
Publicado: (2023) -
A potential biomarker for treatment stratification in psychosis: evaluation of an [(18)F] FDOPA PET imaging approach
por: Veronese, Mattia, et al.
Publicado: (2020) -
The effect of antipsychotics on glutamate levels in the anterior cingulate cortex and clinical response: A (1)H-MRS study in first-episode psychosis patients
por: Zahid, Uzma, et al.
Publicado: (2022) -
The potential of (1)H-MRS in CNS drug development
por: Egerton, Alice
Publicado: (2019)