S180. THE SELECTIVE GPR139 AGONIST TAK-041 REVERSES ANHEDONIA AND SOCIAL INTERACTION DEFICITS IN RODENT MODELS RELATED TO NEGATIVE SYMPTOMS IN SCHIZOPHRENIA

BACKGROUND: Negative symptoms in schizophrenia (SCZ) are poorly treated and interfere with the function of patients. Studies focusing on structural and functional imaging and non-invasive electrophysiology implicate perturbations of the frontocortico-temporal circuits and disruption of cortico-stria...

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Detalles Bibliográficos
Autores principales: Schiffer, Hans, Atienza, Josephine, Reichard, Holly, Mulligan, Victoria, Cilia, Jackie, Monenschein, Holger, Collia, Deanna, Ray, Jim, Kilpatrick, Gavin, Brice, Nicola, Carlton, Mark, Hitchcock, Steve, Corbett, Ged, Hodgson, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Poster Session I
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234360/
http://dx.doi.org/10.1093/schbul/sbaa031.246

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