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M204. ULTRA-RESISTANT SCHIZOPHRENIA IS ASSOCIATED WITH A DELAY TO INITIATE CLOZAPINE AND WITH LESS ABDOMINAL OBESITY. SEX DIFFERENCES IN INSULINEMIA AND LEPTIN LEVELS ARE OBSERVED BETWEEN RESPONDERS AND NOT RESPONDERS
BACKGROUND: 30% patients suffering from schizophrenia fail to obtain therapeutic benefit even after two appropriate antipsychotic trials and are considered resistant. The recommended treatment in these cases is clozapine (CLZ), but only 40% of patients with resistant schizophrenia show clinical resp...
Autores principales: | Hönig, Guillermo, Rodante, Demián, Daray, Federico, Izaguirre, Mercedes, Lenze, Mariela, Valentini, Joaquín, García Bournissen, Facundo, Laura Gutiérrez, María, Wikinski, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234559/ http://dx.doi.org/10.1093/schbul/sbaa030.516 |
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